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AADvac1

8 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

8

Ongoing

4

Recruiting

1

Completed

3

Sites

51

Countries

9

Endpoints

52

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 52 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
3
Phase 2
5

Trials by status

Not yet recruiting
2
By invitation
1
Recruiting
1
Completed
3
Unknown
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Disease progression
10
Neuroimaging
8
Other (unclassified)
7
Global cognition
5
Safety / tolerability / PK
5
Function / daily living
4
Neurodegeneration biomarkers
3
Tau biomarkers
2
Caregiver / quality of life
2
Other clinical outcomes
2
Memory
1
Behavior / neuropsychiatric
1
Amyloid biomarkers
1
Fluid / digital biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 9 of 52 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Neurofilament light (NfL)Neurodeg.

3

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

2

ADAS-CogCognition

2

Neurofilament light (NfL)Amyloid

1

Phosphorylated tau 217 (p-tau217)Progression

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

8 of 8

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
ADAMANT24 Months Safety and Efficacy Study of AADvac1 in Patients With Mild Alzheimer's Disease

AADvac1

Alzheimer’s disease

Alzheimer's diseasePh 2Completed42Jun 20194
FUNDAMANT18-months Safety Follow-up Study of AADvac1, an Active Tau Vaccine for Alzheimer's Disease

AADvac1

Alzheimer’s disease

Age 50-86Ph 1Completed4Aug 20162
AIDAA 24-month Phase 1 Pilot Study of AADvac1 in Patients With Non Fluent Primary Progressive Aphasia

AADvac1

Frontotemporal dementia

Age 18-85Ph 1Unknown3Nov 20203
NCT01850238Safety Study of AADvac1, a Tau Peptide-KLH-Conjugate Active Vaccine to Treat Alzheimer's Disease

AADvac1

Alzheimer’s disease

Alzheimer's diseasePh 1Completed3Mar 20153
ATPAlzheimer's Tau Platform: Regimen A - AADvac1

AADvac1, Donanemab

Alzheimer’s disease

Age 50-80Ph 2By invitation1Aug 2028-
ATPAlzheimer's Tau Platform: Master Protocol

AADvac1

Alzheimer’s disease

Preclinical/asymptomatic ADPh 2Recruiting1Aug 2028-
NCT07217665The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1

AADvac1

Frontotemporal dementia

MMSE ≥25Ph 2Not yet recruiting0Sep 2030-
PTPThe Progressive Supranuclear Palsy Clinical Trial Platform

AADvac1, LM11A-31

Frontotemporal dementia

MMSE ≥25Ph 2Not yet recruiting0Sep 2030-

Showing 1-8 of 8 trials