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Allopregnanolone

3 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

3

Ongoing

1

Recruiting

0

Completed

1

Sites

10

Countries

1

Endpoints

51

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 51 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
2
Phase 2
1

Trials by status

Active, not recruiting
1
Completed
1
Terminated
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
18
Other (unclassified)
8
Global cognition
7
Neuroimaging
6
Behavior / neuropsychiatric
4
Caregiver / quality of life
4
Function / daily living
1
Amyloid biomarkers
1
Fluid / digital biomarkers
1
Other clinical outcomes
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 9 of 51 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

3

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

2

Mini-Mental State Examination (MMSE)Cognition

2

Neuropsychiatric Inventory (NPI)Behavior

1

ADAS-CogOther

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

3 of 3

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
REGEN-BRAIN©Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

Allopregnanolone

Alzheimer’s disease

Alzheimer's diseasePh 2Active, not recruiting9Nov 20264
AlloAllopregnanolone for Mild Cognitive Impairment Due to Alzheimer's Disease or Mild AD

Allopregnanolone

Alzheimer’s disease, MCI / preclinical Alzheimer’s

MCI due to ADPh 1Completed1Feb 20181
Allo-IMAllopregnanolone Regenerative Therapeutic for Early Alzheimer's Disease: Intramuscular Study

Allopregnanolone

Alzheimer’s disease

MCI due to ADPh 1Terminated1Dec 2022-

Showing 1-3 of 3 trials