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AZD3480

7 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

7

Ongoing

0

Recruiting

0

Completed

5

Sites

103

Countries

14

Endpoints

20

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 20 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
5
Phase 2
2

Trials by status

Completed
5
Terminated
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
7
Global cognition
6
Other (unclassified)
5
Behavior / neuropsychiatric
1
Caregiver / quality of life
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 7 of 20 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

4

Mini-Mental State Examination (MMSE)Cognition

2

Neuropsychiatric Inventory (NPI)Behavior

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

7 of 7

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
SiroccoProof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease

AZD3480, Donepezil

Alzheimer’s disease

Alzheimer's diseasePh 2Completed70Aug 2008-
NCT01466088Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD)

AZD3480, Donepezil

Alzheimer’s disease

Alzheimer's diseasePh 2Completed33May 2014-
DDIDrug Interaction Study Between AZD3480 and Warfarin

AZD3480

Alzheimer’s disease

Age 18-45Ph 1Completed1Feb 2009-
NCT00689559Drug Interaction Study Between AZD3480 and Aripiprazole in Healthy Subjects

AZD3480

Alzheimer’s disease

Age 18-45Ph 1Completed1Apr 2009-
MBStudy of Uptake, Break Down and Elimination of an Investigational Drug in Healthy Volunteers

AZD3480

Alzheimer’s disease

Healthy volunteersPh 1Terminated1Oct 2009-
NCT00713765Pharmacokinetic Interaction Between AZD3480 and Donepezil

AZD3480

Alzheimer’s disease

Age 20-60Ph 1Terminated1Dec 2008-
CocktailDrug Interaction Study Between AZD3480 and Cytochrome P450

AZD3480

Alzheimer’s disease

Age 18-55Ph 1Completed1Sep 2008-

Showing 1-7 of 7 trials