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Daridorexant

2 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

2

Ongoing

2

Recruiting

2

Completed

0

Sites

2

Countries

2

Endpoints

53

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 53 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
1
Phase 4
1

Trials by status

Recruiting
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Behavior / neuropsychiatric
27
Other (unclassified)
9
Amyloid biomarkers
6
Global cognition
5
Other clinical outcomes
3
Neurodegeneration biomarkers
1
Fluid / digital biomarkers
1
Safety / tolerability / PK
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 15 of 53 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Neurofilament light (NfL)Amyloid

4

Neuropsychiatric Inventory (NPI)Behavior

3

Mini-Mental State Examination (MMSE)Cognition

3

Phosphorylated tau 217 (p-tau217)Other

2

Phosphorylated tau 181 (p-tau181)Other

2

Montreal Cognitive Assessment (MoCA)Cognition

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

2 of 2

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
PAD-DORADaridorexant for Alzheimer Disease Prevention

Daridorexant

Alzheimer’s disease

MMSE ≥24Ph 2Recruiting1Dec 2028-
DARIDOR-ALZDaridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

Daridorexant

Alzheimer’s disease, MCI / preclinical Alzheimer’s

Alzheimer's diseasePh 4Recruiting1May 2027-

Showing 1-2 of 2 trials