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Divalproex

5 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

5

Ongoing

0

Recruiting

0

Completed

2

Sites

5

Countries

1

Endpoints

16

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 16 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
1
Phase 2
1
Phase 3
1
Phase 4
2

Trials by status

Completed
2
Terminated
1
Withdrawn
1
Unknown
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Behavior / neuropsychiatric
7
Other (unclassified)
7
Global cognition
1
Safety / tolerability / PK
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 2 of 16 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Neuropsychiatric Inventory (NPI)Behavior

1

Mini-Mental State Examination (MMSE)Cognition

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

5 of 5

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT00375557Safety and Efficacy of Divalproex and Quetiapine in Elderly Alzheimer's Dementia Patients

Divalproex, Quetiapine

Alzheimer’s disease

Alzheimer's diseasePh 4Withdrawn1Sep 20071
NCT00315900Depakote Extended Release (ER) Versus Seroquel for Agitated Behaviors in Nursing Home Care Unit Patients With Dementia

Divalproex, Quetiapine

Alzheimer’s disease, Vascular cognitive impairment / dementia, Mixed / unspecified dementia

Multiple dementia etiologiesPh 3Terminated1Dec 20071
NCT00088387Effect of Lithium and Divalproex in Alzheimer's Disease

Divalproex, Lithium

Alzheimer’s disease

Alzheimer's diseasePh 2Completed1Mar 20053
NCT00197834Study of Depakote for Behavioral and Psychological Symptoms in Dementia

Divalproex

Mixed / unspecified dementia

MMSE ≥7Ph 1Unknown1--
NCT00208819A Comparison of Two Standard Therapies in the Management of Dementia With Agitation

Divalproex, Olanzapine, Quetiapine, Risperidone

Alzheimer’s disease

Age ≥65Ph 4Completed1Jul 2007-

Showing 1-5 of 5 trials