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GSK4527226

2 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

2

Ongoing

2

Recruiting

1

Completed

0

Sites

92

Countries

16

Endpoints

16

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 16 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
2

Trials by status

Recruiting
1
Active, not recruiting
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Global cognition
8
Function / daily living
3
Amyloid biomarkers
2
Safety / tolerability / PK
2
Memory
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 12 of 16 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

5

ADCS-Activities of Daily Living (ADCS-ADL)Function

3

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

2

ADAS-CogMemory

1

Mini-Mental State Examination (MMSE)Cognition

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

2 of 2

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
PROGRESS-ADEfficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease

GSK4527226

Alzheimer’s disease

MCI due to AD / mild AD dementiaPh 2Active, not recruiting97Sep 2026-
NCT07105709Open-label Extension Study in Participants With Early Alzheimer's Disease

GSK4527226

Alzheimer’s disease

Age 50-85Ph 2Recruiting33Sep 2028-

Showing 1-2 of 2 trials