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HT-4253

1 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

1

Ongoing

1

Recruiting

0

Completed

0

Sites

1

Countries

1

Endpoints

17

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 17 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
1

Trials by status

Not yet recruiting
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Amyloid biomarkers
8
Safety / tolerability / PK
5
Other (unclassified)
3
Fluid / digital biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 3 of 17 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Phosphorylated tau 217 (p-tau217)Other

2

Phosphorylated tau 181 (p-tau181)Other

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

1 of 1

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT07399171Study to Evaluate the Effect of HT-4253 for the Prevention of Alzheimer's Disease in APOE4 Carriers

HT-4253

Alzheimer’s disease

Amyloid biomarker requiredPh 2Not yet recruiting1May 2027-

Showing 1-1 of 1 trials