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Immunoglobulin

8 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

8

Ongoing

0

Recruiting

0

Completed

5

Sites

145

Countries

8

Endpoints

168

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 168 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
4
Phase 2/3
1
Phase 3
3

Trials by status

Completed
5
Terminated
3

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Global cognition
42
Safety / tolerability / PK
28
Caregiver / quality of life
22
Other (unclassified)
22
Function / daily living
12
Amyloid biomarkers
12
Executive function / language
8
Behavior / neuropsychiatric
8
Memory
6
Neuroimaging
6
Tau biomarkers
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 54 of 168 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

22

ADCS-Activities of Daily Living (ADCS-ADL)Function

10

Mini-Mental State Examination (MMSE)Cognition

10

Neuropsychiatric Inventory (NPI)Behavior

6

Phosphorylated tau 181 (p-tau181)Tau

2

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

2

Phosphorylated tau 181 (p-tau181)Amyloid

2

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

8 of 8

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT01524887Phase 3 IGIV, 10% in Alzheimer´s Disease

Immunoglobulin

Alzheimer’s disease

Alzheimer's diseasePh 3Terminated69Jul 2013-results
NCT00818662A Phase 3 Study Evaluating Safety and Effectiveness of Immune Globulin Intravenous (IGIV 10%) for the Treatment of Mild-to-Moderate Alzheimer´s Disease

Immunoglobulin

Alzheimer’s disease

Alzheimer's diseasePh 3Completed41Dec 20121results
AMBARA Study to Evaluate Albumin and Immunoglobulin in Alzheimer's Disease

Immunoglobulin

Alzheimer’s disease

Alzheimer's diseasePh 2/3Completed40Mar 20182results
NCT03319810Effect of IVIG on Cerebral and Retinal Amyloid in Mild Cognitive Impairment Due to Alzheimer Disease

Immunoglobulin

Alzheimer’s disease, MCI / preclinical Alzheimer’s

MCI due to ADPh 2Completed1Jul 20181results
NCT00812565Study of Octagam (Intravenous Immunoglobulin [IVIG]) 10% on the Treatment of Mild to Moderate Alzheimer's Disease

Immunoglobulin

Alzheimer’s disease

Alzheimer's diseasePh 2Completed1Sep 20101results
NCT01736579Long-Term Study of IGIV, 10% in Alzheimer´s Disease

Immunoglobulin

Alzheimer’s disease

Alzheimer's diseasePh 3Terminated1Jun 2013-results
NCT00299988Phase II Study of Intravenous Immunoglobulin (IVIg) for Alzheimer's Disease

Immunoglobulin

Alzheimer’s disease

Alzheimer's diseasePh 2Terminated1Jan 2009-results
MCIStudy of Intravenous Immunoglobulin in Amnestic Mild Cognitive Impairment

Immunoglobulin

MCI / preclinical Alzheimer’s

MMSE 24-30Ph 2Completed1Mar 20203results

Showing 1-8 of 8 trials