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Lamivudine

2 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

2

Ongoing

1

Recruiting

0

Completed

1

Sites

4

Countries

2

Endpoints

13

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 13 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1/2
1
Phase 2
1

Trials by status

Active, not recruiting
1
Completed
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
5
Other (unclassified)
3
Global cognition
2
Fluid / digital biomarkers
2
Amyloid biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 3 of 13 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Mini-Mental State Examination (MMSE)Cognition

2

Neurofilament light (NfL)Amyloid

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

2 of 2

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
ART-ADPilot Study to Investigate the Safety and Feasibility of AntiRetroviral Therapy for Alzheimer's Disease

Lamivudine

Alzheimer’s disease

Alzheimer's diseasePh 1/2Completed3May 20231results
NCT06519357A Single-center, Self-controlled, Prospective Case Series Pilot Study to Assess the Effect of Lamivudine (3TC) on Neurocognitive Impairment Biomarkers and Type-I IFN (Interferon)-Stimulated Genes in the Plasma of Patients With Mild Cognitive Impairment (MCI)

Lamivudine

MCI / preclinical Alzheimer’s

MCI due to AD / prodromal ADPh 2Active, not recruiting1Sep 2025-

Showing 1-2 of 2 trials