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Lemborexant

4 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

4

Ongoing

2

Recruiting

2

Completed

1

Sites

49

Countries

4

Endpoints

126

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 126 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
3
Phase 4
1

Trials by status

Recruiting
2
Completed
1
Withdrawn
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Behavior / neuropsychiatric
76
Fluid / digital biomarkers
34
Other (unclassified)
4
Amyloid biomarkers
3
Safety / tolerability / PK
3
Executive function / language
2
Tau biomarkers
2
Neurodegeneration biomarkers
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 8 of 126 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Neuropsychiatric Inventory (NPI)Behavior

6

Neurofilament light (NfL)Neurodeg.

2

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

4 of 4

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT03001557Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementia

Lemborexant

Alzheimer’s disease

Alzheimer's diseasePh 2Completed48Jul 2018-results
NCT06274528DORA and LP in Alzheimer's Disease Biomarkers

Lemborexant

Alzheimer’s disease

Age ≥65Ph 2Recruiting1Mar 2030-
NCT05728736Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau

Lemborexant

Alzheimer’s disease

Amyloid biomarker required (plasma)Ph 2Withdrawn1Sep 2023-
NCT06093126Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

Lemborexant

Frontotemporal dementia

-Ph 4Recruiting1Dec 2028-

Showing 1-4 of 4 trials