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Levetiracetam

13 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

13

Ongoing

3

Recruiting

3

Completed

7

Sites

40

Countries

5

Endpoints

145

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 145 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
9
Phase 2/3
1
Phase 3
1
Phase 4
2

Trials by status

Recruiting
3
Completed
7
Withdrawn
1
Unknown
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Global cognition
38
Other (unclassified)
18
Fluid / digital biomarkers
16
Behavior / neuropsychiatric
15
Neuroimaging
15
Executive function / language
10
Other clinical outcomes
9
Safety / tolerability / PK
8
Function / daily living
6
Memory
4
Caregiver / quality of life
3
Neurodegeneration biomarkers
2
Tau biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 37 of 145 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

10

Mini-Mental State Examination (MMSE)Cognition

9

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

7

Montreal Cognitive Assessment (MoCA)Cognition

4

Neuropsychiatric Inventory (NPI)Behavior

4

ADCS-Activities of Daily Living (ADCS-ADL)Function

2

Neurofilament light (NfL)Neurodeg.

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

13 of 13

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
HOPE4MCIStudy of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease

Levetiracetam

Alzheimer’s disease, MCI / preclinical Alzheimer’s

MCI due to ADPh 2/3Completed24Nov 2022-results
LESS-ADLEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down Syndrome

Levetiracetam

Alzheimer’s disease

Age ≥40Ph 3Recruiting5Dec 2027-
ALEVIATE-2Levetiracetam for Persons at Risk for Alzheimer's Disease

Levetiracetam

Alzheimer’s disease

Family history of Alzheimer’s disease requiredPh 2Recruiting2Jan 2027-
LEV-ADLevetiracetam for Alzheimer's Disease-Associated Network Hyperexcitability

Levetiracetam

Alzheimer’s disease

Alzheimer's diseasePh 2Completed2Jul 202016results
NCT05969054Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy

Lacosamide, Levetiracetam

Alzheimer’s disease

MMSE ≥18Ph 4Unknown1Dec 2025-
NCT01044758Levetiracetam and Memory Function in Amnestic Mild Cognitive Impairment (MCI)

Levetiracetam

MCI / preclinical Alzheimer’s

Age 50-85Ph 2Completed1Jul 20127results
NCT05986721Clinical Trial of AGB101 for Mild Cognitive Impairment

Levetiracetam

Alzheimer’s disease, MCI / preclinical Alzheimer’s

MCI due to ADPh 2Withdrawn1Jul 2028-
ILiADAn Investigation of Levetiracetam in Alzheimer's Disease

Levetiracetam

Alzheimer’s disease

mild-to-moderate ADPh 2Completed1Mar 20222
NCT01318408Levetiracetam: The Anti-Convulsant of Choice for Elderly Patients With Dementia

Levetiracetam

Alzheimer’s disease, MCI / preclinical Alzheimer’s, Mixed / unspecified dementia

Multiple dementia etiologiesPh 4Completed1Mar 20081results
LeADTreating Hyperexcitability in AD With Levetiracetam

Levetiracetam

Alzheimer’s disease, MCI / preclinical Alzheimer’s

Alzheimer's diseasePh 2Completed1Feb 20262
AGB101-CNClinical Trial Evaluating the Efficacy of AGB101 for Reducing Hippocampal Overactivity in Older Adults

Levetiracetam

Mixed / unspecified dementia

MMSE 27-30Ph 2Recruiting1May 20275
NCT03461861Network-Level Mechanisms for Preclinical Alzheimer's Disease Development

Levetiracetam

Alzheimer’s disease

MoCA 23Ph 2Completed1Mar 202115results
LAPSELevetiracetam for Alzheimer's Disease Neuropsychiatric Symptoms Related to Epilepsy Trial (LAPSE)

Levetiracetam

Alzheimer’s disease

Alzheimer's diseasePh 2Unknown1Dec 202445

Showing 1-13 of 13 trials