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LY2886721

4 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

4

Ongoing

0

Recruiting

0

Completed

3

Sites

36

Countries

5

Endpoints

56

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 56 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
3
Phase 1/2
1

Trials by status

Completed
3
Terminated
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Amyloid biomarkers
18
Safety / tolerability / PK
18
Fluid / digital biomarkers
10
Global cognition
8
Tau biomarkers
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 6 of 56 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

2

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

2

Mini-Mental State Examination (MMSE)Cognition

2

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

4 of 4

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT01561430Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease

LY2886721

Alzheimer’s disease, MCI / preclinical Alzheimer’s

MCI due to ADPh 1/2Terminated34Aug 2013-results
NCT01227252A Safety Study of LY2886721 Multiple Doses in Healthy Subjects

LY2886721

Alzheimer’s disease

Age ≥20Ph 1Completed1Apr 2011-results
NCT01807026A Study of LY2886721 in Healthy Participants and Participants Diagnosed With Alzheimer's Disease

LY2886721

Alzheimer’s disease

Alzheimer's diseasePh 1Completed1May 2013-results
NCT01133405A Safety Study of LY2886721 Single Doses in Healthy Subjects

LY2886721

Alzheimer’s disease

Age ≥20Ph 1Completed1Oct 2010-results

Showing 1-4 of 4 trials