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Piromelatine

2 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

2

Ongoing

1

Recruiting

0

Completed

1

Sites

90

Countries

2

Endpoints

27

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 27 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
1
Phase 2/3
1

Trials by status

Active, not recruiting
1
Completed
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
11
Global cognition
6
Behavior / neuropsychiatric
4
Function / daily living
3
Other (unclassified)
2
Other clinical outcomes
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 9 of 27 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

3

ADCS-Activities of Daily Living (ADCS-ADL)Function

3

Neuropsychiatric Inventory (NPI)Behavior

2

Mini-Mental State Examination (MMSE)Cognition

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

2 of 2

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT02615002Safety and Efficacy of Piromelatine in Mild Alzheimer's Disease Patients (ReCOGNITION)

Piromelatine

Alzheimer’s disease

Alzheimer's diseasePh 2Completed56Jun 20191results
NCT05267535Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease

Piromelatine

Alzheimer’s disease

Alzheimer's diseasePh 2/3Active, not recruiting37Jun 20251

Showing 1-2 of 2 trials