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RG6289

1 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

1

Ongoing

1

Recruiting

0

Completed

0

Sites

1

Countries

1

Endpoints

5

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 5 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2/3
1

Trials by status

Not yet recruiting
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Amyloid biomarkers
4
Neuroimaging
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 4 of 5 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Amyloid PET CentiloidAmyloid

2

Phosphorylated tau 217 (p-tau217)Amyloid

2

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

1 of 1

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT06996730A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease

Donanemab, RG6289

Alzheimer’s disease

mild AD dementia · PSEN1 mutation requiredPh 2/3Not yet recruiting1Jun 2030-

Showing 1-1 of 1 trials