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Sargramostim

3 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

3

Ongoing

1

Recruiting

1

Completed

1

Sites

3

Countries

1

Endpoints

28

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 28 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
3

Trials by status

Recruiting
1
Completed
1
Withdrawn
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Global cognition
9
Executive function / language
5
Safety / tolerability / PK
4
Function / daily living
3
Amyloid biomarkers
2
Memory
1
Behavior / neuropsychiatric
1
Neuroimaging
1
Fluid / digital biomarkers
1
Other (unclassified)
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 14 of 28 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Mini-Mental State Examination (MMSE)Cognition

3

ADCS-Activities of Daily Living (ADCS-ADL)Function

3

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

3

ADAS-CogCognition

2

ADAS-CogMemory

1

Montreal Cognitive Assessment (MoCA)Cognition

1

Neuropsychiatric Inventory (NPI)Behavior

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

3 of 3

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT02667496Safety Study of Sargramostim in Treating Patients With Mild Cognitive Impairment Due to Alzheimer's Disease

Sargramostim

Alzheimer’s disease, MCI / preclinical Alzheimer’s

MCI due to ADPh 2Withdrawn1Mar 2017-
NCT01409915Study of the Safety & Efficacy of Leukine® in the Treatment of Alzheimer's Disease

Sargramostim

Alzheimer’s disease

mild-to-moderate ADPh 2Completed1Dec 2019-results
SESADPhase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease

Sargramostim

Alzheimer’s disease

Alzheimer's diseasePh 2Recruiting1Nov 20261

Showing 1-3 of 3 trials