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Sertraline

6 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

6

Ongoing

0

Recruiting

0

Completed

6

Sites

15

Countries

3

Endpoints

32

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 32 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
1
Phase 2/3
1
Phase 4
3
Not applicable
1

Trials by status

Completed
6

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Behavior / neuropsychiatric
13
Other (unclassified)
12
Global cognition
3
Other clinical outcomes
3
Caregiver / quality of life
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 2 of 32 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Neuropsychiatric Inventory (NPI)Behavior

2

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

6 of 6

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
DESEPDementia Antipsychotics And Antidepressants Discontinuation Study

Citalopram, Escitalopram, Paroxetine, Risperidone, Sertraline

Alzheimer’s disease, Vascular cognitive impairment / dementia

Multiple dementia etiologiesPh 4Completed8Dec 20101
DIADS-2Depression in Alzheimer's Disease-2

Sertraline

Alzheimer’s disease

Alzheimer's diseasePh 2/3Completed5Jul 20083results
CCICAMH - McMaster Collaborative Care Initiative For Mental Health Risk Factors In Dementia

Sertraline, Venlafaxine

Mixed / unspecified dementia

Age 60-65Not applicableCompleted1Jul 20201
NCT00001777Sertraline for the Treatment of Patients With Frontal Lobe Dementia (FLD)

Sertraline

Mixed / unspecified dementia

-Ph 1Completed1May 20003
NCT00009191The Depression in Alzheimer's Disease Study (DIADS)

Sertraline

Alzheimer’s disease

Alzheimer's diseasePh 4Completed1Nov 20061
NCT00433121Discontinuation of Antipsychotics and Antidepressants Among Patients With BPSD

Citalopram, Escitalopram, Haloperidol, Olanzapine, Quetiapine, Risperidone, Sertraline

Alzheimer’s disease, Vascular cognitive impairment / dementia

Multiple dementia etiologiesPh 4Completed1Aug 2007-

Showing 1-6 of 6 trials