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Simenafil Hydrochloride

1 trials in this asset. Source: ClinicalTrials.gov, as of November 5, 2026.

Trials

1

Ongoing

1

Recruiting

0

Completed

0

Sites

1

Countries

1

Endpoints

15

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 15 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 2
1

Trials by status

Not yet recruiting
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Amyloid biomarkers
4
Global cognition
3
Other (unclassified)
3
Neurodegeneration biomarkers
2
Function / daily living
1
Behavior / neuropsychiatric
1
Safety / tolerability / PK
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 8 of 15 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

1

ADAS-CogCognition

1

ADCS-Activities of Daily Living (ADCS-ADL)Function

1

Mini-Mental State Examination (MMSE)Cognition

1

Phosphorylated tau 181 (p-tau181)Other

1

Phosphorylated tau 217 (p-tau217)Other

1

Neurofilament light (NfL)Neurodeg.

1

Amyloid PET CentiloidAmyloid

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

1 of 1

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT07905352A Phase 2 Clinical Study of Simenafil Hydrochloride Tablets in the Treatment of Alzheimer's Disease

Simenafil Hydrochloride

Alzheimer’s disease

MCI due to AD / mild AD dementiaPh 2Not yet recruiting1Sep 2028-

Showing 1-1 of 1 trials