Simvastatin
6 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.
Trials
6
Ongoing
0
Recruiting
0
Completed
6
Sites
48
Countries
1
Endpoints
38
Composite endpoints
0
Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 38 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.
Development
Where the program stands
Trials by phase
Trials by status
Evidence coverage
What this asset has been measured on
Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.
Most-measured metrics
Top 20 metrics across this asset's endpoints
Normalized metric codes are available for 6 of 38 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.
2
2
2
Trials
Trials for this asset
Every trial for this asset, with the same search, filters, and sort as the Trials tab.
6 of 6
| Asset / Disease area | Key I/E criterion | Evidence | ||||||
|---|---|---|---|---|---|---|---|---|
| NCT00053599Cholesterol Lowering Agent to Slow Progression (CLASP) of Alzheimer's Disease Study | Simvastatin Alzheimer’s disease | Alzheimer's disease | Ph 3 | Completed | 44 | Oct 2007 | 3 | |
| SHARPStatin Effects on Beta-Amyloid and Cerebral Perfusion in Adults at Risk for Alzheimer's Disease | Simvastatin Alzheimer’s disease | Alzheimer's disease | Ph 2 | Completed | 1 | Sep 2013 | 2 | results |
| ESPRITEvaluating Simvastatin's Potential Role in Therapy | Simvastatin Alzheimer’s disease | Age 35-69 | Ph 2 | Completed | 1 | Jun 2009 | 3 | results |
| NCT00303277Do HMG CoA Reductase Inhibitors Affect Abeta Levels? | pravastatin, Simvastatin Alzheimer’s disease | Age 18-90 | Ph 4 | Completed | 1 | Apr 2005 | 3 | |
| NCT01439555Endothelial Facilitation in Alzheimer's Disease | Simvastatin, Tetrahydrobiopterin Alzheimer’s disease | MMSE 15-26 | Ph 2 | Completed | 1 | Nov 2017 | 1 | results |
| SimBioEffects of Simvastatin on Biomarkers | Simvastatin Alzheimer’s disease | MMSE ≥26 | Ph 4 | Completed | 1 | Oct 2015 | - | results |
Showing 1-6 of 6 trials