Skip to main content
Delfa

← All assets

TPI-287

2 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

2

Ongoing

0

Recruiting

0

Completed

2

Sites

3

Countries

1

Endpoints

15

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 15 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
2

Trials by status

Completed
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Global cognition
3
Safety / tolerability / PK
3
Behavior / neuropsychiatric
2
Neuroimaging
2
Fluid / digital biomarkers
2
Function / daily living
1
Amyloid biomarkers
1
Tau biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 5 of 15 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADAS-CogCognition

1

ADCS-Activities of Daily Living (ADCS-ADL)Function

1

Neurofilament light (NfL)Tau

1

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

1

Mini-Mental State Examination (MMSE)Cognition

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

2 of 2

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
TPI-287-4RTSafety Study of TPI-287 to Treat CBS and PSP

TPI-287

Frontotemporal dementia

MMSE 14-30Ph 1Completed2Sep 20196
NCT01966666A Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of TPI-287 in Alzheimer's Disease

TPI-287

Alzheimer’s disease

Alzheimer's diseasePh 1Completed1Sep 20191

Showing 1-2 of 2 trials