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XPro1595

4 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

4

Ongoing

0

Recruiting

0

Completed

2

Sites

49

Countries

8

Endpoints

52

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 52 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
1
Phase 2
3

Trials by status

Completed
2
Terminated
1
Withdrawn
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Global cognition
10
Other (unclassified)
9
Neuroimaging
6
Behavior / neuropsychiatric
5
Memory
4
Safety / tolerability / PK
4
Executive function / language
3
Function / daily living
3
Amyloid biomarkers
3
Tau biomarkers
2
Fluid / digital biomarkers
1
Caregiver / quality of life
1
Other clinical outcomes
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 11 of 52 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Neuropsychiatric Inventory (NPI)Behavior

5

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

4

Mini-Mental State Examination (MMSE)Cognition

1

ADCS-Activities of Daily Living (ADCS-ADL)Function

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

4 of 4

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
MINDFuLA Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation

XPro1595

Alzheimer’s disease, MCI / preclinical Alzheimer’s

Alzheimer's diseasePh 2Completed41May 20254results
NCT03943264A Biomarker-directed Study of XPro1595 in Patients With Alzheimer's

XPro1595

Alzheimer’s disease

Alzheimer's diseasePh 1Completed5Jun 20214
NCT05522387An Open-Label Extension of XPro1595 in Patients With Alzheimer's Disease

XPro1595

Alzheimer’s disease

Study partner/caregiver requiredPh 2Terminated4Jun 202442
NCT05321498Study to Assess the Efficacy of XPro1595 in Patients With Mild Cognitive Impairment With Biomarkers of Inflammation

XPro1595

Alzheimer’s disease, MCI / preclinical Alzheimer’s

Alzheimer's diseasePh 2Withdrawn0Oct 20234

Showing 1-4 of 4 trials