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Subcutaneous · GLP-1 / GIP dual

CT-388

7 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

7

Active

5

Recruiting

2

Completed

2

Sites

187

Countries

16

Endpoints

169

Composite endpoints

2

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
2
Phase 2
3
Phase 3
2

Trials by status

Not yet recruiting
2
Recruiting
2
Active, not recruiting
1
Completed
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Weight & body composition
60
Glycemic / diabetes
35
Cardiometabolic biomarkers
33
Patient-reported / QoL
22
Safety / tolerability / PK
16
Other (unclassified)
2
Renal / kidney
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Body weight, % changeWeight

13

PGI, changePRO/QoL

8

HbA1c, changeGlycemic

7

Body weight, absolute change (kg)Weight

6

≥5% weight-loss respondersWeight

5

Waist circumference, changeWeight

5

Fasting glucose, changeGlycemic

5

BMI, changeWeight

5

Treatment-emergent AEs (any)Safety/PK

4

HbA1c <6.5% achievementGlycemic

3

LDL-C, changeBiomarker

3

HDL-C, changeBiomarker

3

Triglycerides, changeBiomarker

3

Systolic BP, changeBiomarker

3

Non-HDL cholesterol, changeBiomarker

3

VLDL, changeBiomarker

3

Total cholesterol, changeBiomarker

3

Free fatty acids, changeBiomarker

3

Diastolic BP, changeBiomarker

3

hs-CRP, changeBiomarker

3

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

7 of 7

Asset / PopulationKey I/E criterionEvidence
Enith1A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

CT-388

Obesity / overweight

Ph 3Recruiting73Jul 2028
NCT06628362A Study of Enicepatide (CT-388) in Participants Who Are Overweight or Obese With Type 2 Diabetes Mellitus

CT-388

Obesity / overweight, Type 2 diabetes

BMI ≥25Ph 2Active, not recruiting70Jun 2026
Enith2A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

CT-388

Obesity / overweight, Type 2 diabetes

BMI ≥27Ph 3Recruiting61Aug 2028
NCT06525935A Study of Enicepatide (CT-388) in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity

CT-388

Obesity / overweight

BMI 27-30Ph 2Completed34Dec 2025
NCT04838405A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus

CT-388

Obesity / overweight, Type 2 diabetes

BMI 27-40Ph 1Completed2Jun 2024
ZYNERGYA Dose-Finding Study of Petrelintide With Enicepatide (RO7795068) in Adults With Obesity or Overweight

CT-388, Petrelintide

Obesity / overweight

BMI ≥30Ph 2Not yet recruiting0Nov 2027
NCT07626515A Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Enicepatide in Generally Healthy Adult Chinese Participants

CT-388

Healthy volunteers, Obesity / overweight

BMI ≥23Ph 1Not yet recruiting0Apr 2027