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Subcutaneous · GLP-1 / GIP dual

CT-868

4 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

4

Active

0

Recruiting

0

Completed

4

Sites

28

Countries

2

Endpoints

45

Composite endpoints

0

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
2
Phase 2
2

Trials by status

Completed
4

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Glycemic / diabetes
22
Weight & body composition
12
Cardiometabolic biomarkers
6
Safety / tolerability / PK
5

Most-measured metrics

Top 20 metrics across this asset's endpoints

HbA1c, changeGlycemic

4

HbA1c <7.0% achievementGlycemic

2

HbA1c <6.5% achievementGlycemic

2

HbA1c <5.7% achievementGlycemic

2

Body weight, absolute change (kg)Weight

2

HOMA-IR (insulin sensitivity)Glycemic

2

CGM time-in-rangeGlycemic

1

CGM time-below-rangeSafety/PK

1

CGM time-above-rangeGlycemic

1

AUC₀–∞Safety/PK

1

Waist circumference, changeWeight

1

BMI, changeWeight

1

Body weight, % changeWeight

1

≥5% weight-loss respondersWeight

1

≥10% weight-loss respondersWeight

1

≥15% weight-loss respondersWeight

1

≥20% weight-loss respondersWeight

1

Fasting glucose, changeGlycemic

1

Total cholesterol, changeBiomarker

1

Triglycerides, changeBiomarker

1

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

4 of 4

Asset / PopulationKey I/E criterionEvidence
NCT06062069A Study of CT-868 in Type 1 Diabetes Mellitus

CT-868

Obesity / overweight, Type 1 diabetes

BMI ≥27Ph 2Completed22Jul 2025
NCT05110846A Study of CT-868 in Overweight and Obese Participants With Type 2 Diabetes Mellitus

CT-868

Obesity / overweight, Type 2 diabetes

BMI ≥27Ph 2Completed5Feb 2023
NCT04973111A Study to Assess CT-868 and the Relationship Between Insulin Secretory Response and Ambient Blood Glucose

CT-868

Obesity / overweight, Type 2 diabetes

BMI 30-35Ph 1Completed1Apr 2022
NCT05794581A Study to Assess the Effects of CT-868 Treatment on Glucose Homeostasis in Participants with Type 1 Diabetes

CT-868, Liraglutide

Obesity / overweight, Type 1 diabetes

BMI 25-35Ph 1Completed1Mar 2024