← All assets

Subcutaneous · GLP-1 / GLP-2 dual

Dapiglutide

5 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

5

Active

1

Recruiting

0

Completed

3

Sites

2

Countries

2

Endpoints

115

Composite endpoints

3

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Early Phase 1
2
Phase 1
2
Phase 2
1

Trials by status

Active, not recruiting
1
Completed
3
Terminated
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
69
Cardiometabolic biomarkers
18
Glycemic / diabetes
12
Weight & body composition
8
MASH / liver
4
Patient-reported / QoL
2
Other (unclassified)
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

AUC₀–∞Safety/PK

11

TmaxSafety/PK

8

CmaxSafety/PK

7

Treatment-emergent AEs (any)Safety/PK

5

Postprandial glucoseGlycemic

5

Half-lifeSafety/PK

4

Free fatty acids, changeBiomarker

4

Triglycerides, changeBiomarker

4

Systolic BP, changeBiomarker

3

Heart rate, changeBiomarker

3

Plasma concentration (steady state)Safety/PK

2

Body weight, % changeWeight

2

Immunogenicity (ADA)Safety/PK

2

Body weight, absolute change (kg)Weight

1

≥5% weight-loss respondersWeight

1

≥10% weight-loss respondersWeight

1

hs-CRP, changeBiomarker

1

≥15% weight-loss respondersWeight

1

BMI, changeWeight

1

Diastolic BP, changeBiomarker

1

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

5 of 5

Asset / PopulationKey I/E criterionEvidence
NCT06000891A Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Dapiglutide, GLP-1 / incretin class catch-all

Obesity / overweight

BMI 27-39.9Ph 1Terminated1Feb 2025
DREAMDapiglutide for the Treatment of Obesity

Dapiglutide

Obesity / overweight

BMI ≥30Ph 2Active, not recruiting1Apr 20241
NCT03994549A Single Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Dapiglutide, GLP-1 / incretin class catch-all

Healthy volunteers

BMI 18.5-28Early Ph 1Completed1Nov 2020
NCT06758583A Trial Comparing Pharmacokinetics, Safety and Tolerability of Two Subcutaneous Concentrations of Dapiglutide

Dapiglutide

Obesity / overweight

BMI ≥27Ph 1Completed1Apr 2025
NCT04612517A Multiple Ascending Dose Trial Assessing Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ZP7570

Dapiglutide

Healthy volunteers

BMI 18.5-28Early Ph 1Completed1Aug 2021