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Subcutaneous · GLP-1 / GIP / glucagon triple

Efocipegtrutide

3 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

3

Active

1

Recruiting

0

Completed

2

Sites

62

Countries

2

Endpoints

7

Composite endpoints

0

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
2
Phase 2
1

Trials by status

Active, not recruiting
1
Completed
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
3
Weight & body composition
1
MASH / liver
1
Renal / kidney
1
Cardiometabolic biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Treatment-emergent AEs (any)Safety/PK

2

Systolic BP, changeBiomarker

1

BMI, changeWeight

1

MASH resolution, no fibrosis worseningMASH

1

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

3 of 3

Asset / PopulationKey I/E criterionEvidence
NCT04505436Study to Evaluate Efficacy, Safety and Tolerability of HM15211(Efocipegtrutide) in Subjects

Efocipegtrutide

MASH / NAFLD / liver fibrosis

BMI ≥18Ph 2Active, not recruiting60Jun 2026
NCT03374241A First-in-human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HM15211(Efocipegtrutide)

Efocipegtrutide

Healthy volunteers, Obesity / overweight

Ph 1Completed1Sep 2018results
NCT03744182A Study of Multiple Doses of HM15211(Efocipegtrutide) in Obese Subjects With NAFLD

Efocipegtrutide

MASH / NAFLD / liver fibrosis, Obesity / overweight

BMI ≥30Ph 1Completed1Mar 2020results