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Subcutaneous · GLP-1 / FGF21 dual

HEC88473

4 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

4

Active

1

Recruiting

1

Completed

3

Sites

5

Countries

2

Endpoints

34

Composite endpoints

1

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
2
Phase 2
2

Trials by status

Recruiting
1
Completed
3

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
12
Other (unclassified)
9
Glycemic / diabetes
6
Weight & body composition
3
Cardiometabolic biomarkers
2
Patient-reported / QoL
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

HbA1c, changeGlycemic

1

Body weight, absolute change (kg)Weight

1

Fasting glucose, changeGlycemic

1

Serious AEs (any)Safety/PK

1

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

4 of 4

Asset / PopulationKey I/E criterionEvidence
NCT06148649Phase 2 Study of HEC88473 Injection in Subjects With Type 2 Diabetes Mellitus

Dulaglutide, HEC88473

Type 2 diabetes

HbA1c 7.5-10.5%Ph 2Completed2Feb 2025
NCT07616037Efficacy of a GLP-1/FGF21 Dual Agonist for Treating PCOS

HEC88473

PCOS

FemalePh 2Recruiting1Jun 2027
NCT04829123The Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of HEC88473 in Healthy Subjects

HEC88473

Healthy volunteers

BMI 18-40Ph 1Completed1Mar 2022
NCT05943886A Phase 1 Study of HEC88473 Injection in Healthy Subjects, Obese Subjects and T2DM Subjects

HEC88473

Healthy volunteers, Obesity / overweight, Type 2 diabetes

BMI ≤28Ph 1Completed1Feb 20232