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Oral · GLP-1 agonist

MDR-001

6 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

6

Active

6

Recruiting

1

Completed

0

Sites

57

Countries

1

Endpoints

78

Composite endpoints

2

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
3
Phase 1/2
1
Phase 2
1
Phase 3
1

Trials by status

Not yet recruiting
5
Recruiting
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
36
Weight & body composition
20
Cardiometabolic biomarkers
14
Glycemic / diabetes
6
Other (unclassified)
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

CmaxSafety/PK

2

AUC₀–∞Safety/PK

2

TmaxSafety/PK

2

Half-lifeSafety/PK

2

Heart rate, changeBiomarker

2

Treatment-emergent AEs (any)Safety/PK

1

Thyroid eventSafety/PK

1

Systolic BP, changeBiomarker

1

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

6 of 6

Asset / PopulationKey I/E criterionEvidence
NCT07274137A Phase III Study to Evaluate the Efficacy and Safety of MDR-001 in Adult Participants With Overweight or Obesity (MOBILE)

MDR-001

Obesity / overweight

BMI ≥28Ph 3Not yet recruiting45Jun 2027
NCT06606483A Study to Evaluate the Efficacy and Safety of MDR-001 in Subjects Who Are Obesity or Overweight

MDR-001

Obesity / overweight

HbA1c ≤6.5%Ph 2Not yet recruiting19Jul 2025
NCT07550621Drug-Drug Interaction Study of MDR-001 With Rifampin and Itraconazole in Healthy Adult Participants

MDR-001

Healthy volunteers

BMI 18-28Ph 1Not yet recruiting1May 2026
NCT07110766Phase Ib Clinical Study on the Efficacy and Safety of MDR-001 in Patients Who Are Obesity or Overweight

MDR-001

Obesity / overweight

BMI ≥28Ph 1Not yet recruiting1Sep 2025
NCT06778850A Phase I/IIa Clinical Study to Assess the Single and Multiple Ascending Doses of MDR-001 Tablets in Healthy Participants and Obese/ Overweight Participants

MDR-001

Healthy volunteers, Obesity / overweight

BMI ≤45Ph 1/2Recruiting1Jul 2025
NCT07550634Pharmacokinetics and Safety of MDR-001 in Mild and Moderate Hepatic Impairment

MDR-001

Healthy volunteers, Hepatic impairment

BMI 18-32Ph 1Not yet recruiting1Jul 2026