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Subcutaneous · GLP-1 / GIP dual

NNC0519-0130

11 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

11

Active

1

Recruiting

1

Completed

10

Sites

274

Countries

20

Endpoints

91

Composite endpoints

0

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
8
Phase 2
3

Trials by status

Recruiting
1
Completed
10

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
46
Weight & body composition
15
Cardiometabolic biomarkers
14
Glycemic / diabetes
7
Renal / kidney
5
Patient-reported / QoL
4

Most-measured metrics

Top 20 metrics across this asset's endpoints

AUC₀–∞Safety/PK

15

Treatment-emergent AEs (any)Safety/PK

14

CmaxSafety/PK

10

HbA1c, changeGlycemic

4

Plasma concentration (steady state)Safety/PK

4

Body weight, % changeWeight

3

Waist circumference, changeWeight

3

Systolic BP, changeBiomarker

3

uACR, changeRenal

3

IWQOL-Lite physicalPRO/QoL

3

Body weight, absolute change (kg)Weight

2

Fasting glucose, changeGlycemic

2

hs-CRP, changeBiomarker

2

Total cholesterol, changeBiomarker

2

HDL-C, changeBiomarker

2

LDL-C, changeBiomarker

2

Triglycerides, changeBiomarker

2

eGFR, changeRenal

2

≥5% weight-loss respondersWeight

2

≥10% weight-loss respondersWeight

2

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

11 of 11

Asset / PopulationKey I/E criterionEvidence
NCT06717698A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

NNC0519-0130, Semaglutide

Chronic kidney disease, Obesity / overweight

Ph 2Recruiting147Sep 2026
NCT06326047A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 Diabetes

NNC0519-0130, Tirzepatide

Type 2 diabetes

HbA1c 7.5-10%Ph 2Completed94Sep 2025
NCT06326060A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose Weight

NNC0519-0130, Tirzepatide

Obesity / overweight

BMI ≥27Ph 2Completed70Apr 2025
NCT05363774A Research Study of a New Medicine NNC0519-0130 in Healthy People, People With High Body Weight and People With Type 2 Diabetes.

NNC0519-0130

Healthy volunteers, Obesity / overweight, Type 2 diabetes

Healthy volunteersPh 1Completed3Apr 2024
NCT06642571A Research Study to Compare How Much of the Medicine NNC0519-0130 is in the Blood of People With Overweight or Obesity Who Receive 2 Preparations of the Medicine

NNC0519-0130

Obesity / overweight

Ph 1Completed1May 2025
NCT07004322A Research Study of the New Medicine NNC0519-0130 in Male Chinese Participants Living With Excess Body Weight

NNC0519-0130

Obesity / overweight

BMI 24-39.9Ph 1Completed1Jan 2026
NCT06718998A Research Study Comparing Different Ways of Increasing the Dose of NNC0519-0130 in Participants With Overweight or Obesity

NNC0519-0130

Obesity / overweight

BMI 27-44.9Ph 1Completed1Jan 2026
NCT06370819A Research Study Looking Into Blood Levels of the Medicine NNC0519-0130 in the Body in Participants With Normal or Reduced Kidney Function

NNC0519-0130

Healthy volunteers, Renal impairment

BMI 20-39.9Ph 1Completed1Nov 2024
NCT06513104A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After Menopause

NNC0519-0130

Healthy volunteers, Obesity / overweight

BMI 27-39.9Ph 1Completed1Sep 2025
NCT06567041A Research Study of How Safe a New Medicine Called NNC0519 0130 is and to Test Its Effect in People Living With Excess Body Weight With or Without Type 2 Diabetes

NNC0519-0130

Obesity / overweight, Type 2 diabetes

Ph 1Completed1Dec 2025
NCT05870670A Research Study of a New Medicine NNC0519-0130 in Japanese and Non-Japanese Men

NNC0519-0130

Healthy volunteers, Obesity / overweight

MalePh 1Completed1Oct 2023