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Oral · GLP-1 agonist

Noiiglutide / HS-20004 / SHR20004

9 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

9

Active

1

Recruiting

0

Completed

5

Sites

7

Countries

1

Endpoints

91

Composite endpoints

0

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
5
Phase 2
3
Phase 3
1

Trials by status

Active, not recruiting
1
Completed
5
Unknown
3

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
40
Glycemic / diabetes
32
Weight & body composition
10
Other (unclassified)
6
Cardiometabolic biomarkers
3

Most-measured metrics

Top 20 metrics across this asset's endpoints

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

9 of 9

Asset / PopulationKey I/E criterionEvidence
NCT04799327The Effect of SHR20004(Noiiglutide ) on Body Weight in Obese Subjects Without Diabetes

Noiiglutide / HS-20004 / SHR20004

Obesity / overweight

BMI 28-40Ph 2Unknown2May 2022
NCT05333835A Trial Comparing the Efficacy and Safety of HR17031 Injection to INS068 Injection and to SHR20004 Injection in Patients With Type 2 Diabetes

Noiiglutide / HS-20004 / SHR20004

Type 2 diabetes

BMI 20-40Ph 2Unknown1Mar 2024
NCT06137469Assessment of Gastric Emptying by SHR20004 in Healthy Subjects

Noiiglutide / HS-20004 / SHR20004

Healthy volunteers

BMI 19-28Ph 1Completed1Mar 2024
NCT05031871Pharmacokinetics of HR17031 Injection in Healthy Subjects

Noiiglutide / HS-20004 / SHR20004

Healthy volunteers

BMI 18-27Ph 1Completed1Nov 2021
NCT06649773The Experiment of Noiiglutide Injection in Type 2 Diabetes Patients

Noiiglutide / HS-20004 / SHR20004

Type 2 diabetes

BMI ≤45Ph 3Active, not recruiting1May 2025
NCT02750007Tolerability to HS-20004 With Titration Administration in Type 2 Diabetic Patients

Noiiglutide / HS-20004 / SHR20004

Type 2 diabetes

BMI 18.5-30Ph 1Unknown1Jan 2017
NCT03848793A Phase 2 Study to Evaluate the Efficacy and Safety of HS-20004 in Type 2 Diabetes Subjects.

Noiiglutide / HS-20004 / SHR20004

Type 2 diabetes

BMI 23-35Ph 2Completed1Jun 2020
NCT02746302Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of HS-20004 in Healthy Chinese Volunteers

Noiiglutide / HS-20004 / SHR20004

Healthy volunteers

BMI 19-24Ph 1Completed0Jan 2014
NCT02746315Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple s.c Doses HS-20004 in Healthy Chinese Volunteers

Noiiglutide / HS-20004 / SHR20004

Healthy volunteers

BMI 19-28Ph 1Completed0Feb 2015