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Subcutaneous · GLP-1 / GIP dual

VK2735

5 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

5

Active

2

Recruiting

0

Completed

3

Sites

148

Countries

3

Endpoints

12

Composite endpoints

5

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 1
1
Phase 2
2
Phase 3
2

Trials by status

Active, not recruiting
2
Completed
3

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Weight & body composition
8
Safety / tolerability / PK
4

Most-measured metrics

Top 20 metrics across this asset's endpoints

Body weight, % changeWeight

4

Treatment-emergent AEs (any)Safety/PK

3

CmaxSafety/PK

1

≥5% weight-loss respondersWeight

1

≥20% weight-loss respondersWeight

1

≥10% weight-loss respondersWeight

1

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

5 of 5

Asset / PopulationKey I/E criterionEvidence
VANQUISH 1VK2735 for Weight Management Phase 3

VK2735

Obesity / overweight

BMI ≥30Ph 3Active, not recruiting137Jul 2027
NCT07104383VK2735 for Weight Management Type 2 Diabetes Phase 3 (VANQUISH 2)

VK2735

Obesity / overweight, Type 2 diabetes

BMI ≥27Ph 3Active, not recruiting127Jul 2027
VENTUREVK2735 for Weight Management Phase 2

VK2735

Obesity / overweight

BMI ≥30Ph 2Completed20Feb 20241
NCT06828055VK2735 for Weight Management Phase 2 (Venture Oral Dosing)

VK2735

Obesity / overweight

BMI ≥30Ph 2Completed15Jun 2025
NCT05203237Phase 1 Study to Evaluate the Safety and Tolerability of VK2735

VK2735

Healthy volunteers, Obesity / overweight

Healthy volunteersPh 1Completed1Nov 2024