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Subcutaneous · GLP-1 agonist

Albiglutide

41 trials in this molecule. Source: ClinicalTrials.gov, as of July 6, 2026.

Trials

41

Ongoing

3

Recruiting

0

Completed

33

Sites

1,396

Countries

41

Endpoints

530

Composite endpoints

43

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Where the program stands

Trials by phase

Phase 1
9
Phase 2
7
Phase 3
15
Phase 4
6
Not applicable
4

Trials by status

Not yet recruiting
1
Active, not recruiting
2
Completed
33
Terminated
3
Withdrawn
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Glycemic / diabetes
190
Safety / tolerability / PK
175
Weight & body composition
39
Cardiometabolic biomarkers
27
Cardiovascular outcomes
23
Renal / kidney
23
Other clinical outcomes
18
Patient-reported / QoL
16
Other (unclassified)
15
Heart failure
3
MASH / liver
1

Top 20 metrics across this asset's endpoints

HbA1c, changeGlycemic

50

Fasting glucose, changeGlycemic

38

Body weight, absolute change (kg)Weight

37

HbA1c <6.5% achievementGlycemic

23

HbA1c <7.0% achievementGlycemic

16

Documented hypoglycemiaSafety/PK

14

Postprandial glucoseGlycemic

11

Plasma concentration (steady state)Safety/PK

9

Heart rate, changeBiomarker

8

Treatment-emergent AEs (any)Safety/PK

8

Serious AEs (any)Safety/PK

7

AUC₀-∞Safety/PK

7

Discontinuation due to AESafety/PK

6

C-peptide AUCGlycemic

5

NauseaSafety/PK

5

Immunogenicity (ADA)Safety/PK

5

Expanded / custom MACE compositeCV

4

eGFR, changeRenal

4

CmaxSafety/PK

4

All-cause deathCV

3

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

41 of 41

GLP-1 and incretin trials
Asset / PopulationEligibility highlightEvidence
NCT02465515Effect of Albiglutide, When Added to Standard Blood Glucose Lowering Therapies, on Major Cardiovascular Events in Subjects With Type 2 Diabetes Mellitus

Albiglutide

Cardiovascular disease, Type 2 diabetes

Established CVDPh 4Completed607Feb 20187results
NCT00838903Efficacy and Safety of Albiglutide in Treatment of Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed386Jan 20121results
NCT00839527A Study to Determine the Safety and Efficacy of Albiglutide in Subjects With Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed358Jan 20123results
NCT00838916A Study to Determine the Safety and Efficacy of Albiglutide in Patients With Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed337Jan 20124results
NCT00849056Safety and Efficacy of Albiglutide in Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed331Nov 20111results
NCT00849017Safety and Efficacy Study of Albiglutide in Type 2 Diabetes

Albiglutide

Type 2 diabetes

BMI 20-45Ph 3Completed262Nov 20114results
NCT01098539A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.

Albiglutide

Renal impairment, Type 2 diabetes

HbA1c 7-10%Ph 3Completed218Nov 20122results
NCT00976391A Study to Determine the Safety and Efficacy of Albiglutide Administered in Combination With Insulin Glargine

Albiglutide

Type 2 diabetes

HbA1c ≤7%Ph 3Completed209Oct 20111results
NCT01128894A Study to Determine the Efficacy and Safety of Albiglutide as Compared With Liraglutide.

Albiglutide, Liraglutide

Type 2 diabetes

HbA1c 7-10%Ph 3Completed173Sep 20111results
NCT00518115Out-Patient Study in Patients With Type 2 Diabetes Mellitus Who Are Taking no Diabetes Medication or Metformin Only

Albiglutide, Exenatide

Type 2 diabetes

BMI 20-40Ph 2Completed163May 20082results
NCT02229227Safety and Efficacy of Albiglutide + Insulin Glargine Versus Insulin Lispro + Insulin Glargine Subjects With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

BMI ≤40Ph 3Completed157Jul 20171results
LixiLan-GEfficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period

Albiglutide, Dulaglutide, Exenatide, GLP-1 / incretin class catch-all, Liraglutide, Lixisenatide

Type 2 diabetes

-Ph 3Completed124May 20185results
NCT01733758A Monotherapy Study to Evaluate the Efficacy and Safety of 2 Dose Levels of Albiglutide in Japanese Subjects With Type 2 Diabetes Mellitus (T2DM)

Albiglutide, Liraglutide

Type 2 diabetes

BMI 17-40Ph 3Completed74Jun 2014-results
NCT02683746Safety and Efficacy Study of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

BMI ≤40Ph 3Completed70Apr 20171results
NCT01777282A Study to Determine the Long Term Safety and Efficacy of Albiglutide in Combination With Oral Monotherapy Antihyperglycemic Medications in Japanese Patients With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

BMI 17-40Ph 3Completed49Jan 20151results
NCT02284009Albiglutide Versus Placebo in Insulin-treated Subjects With New-onset Type 1 Diabetes Mellitus

Albiglutide

Type 1 diabetes

BMI ≤32Ph 2Completed32Oct 20171results
NCT01098461Dose Ranging Study of Albiglutide in Japanese Subjects

Albiglutide

Type 2 diabetes

BMI 18-35Ph 2Completed30May 20112results
NCT01357889Pharmacokinetics/Pharmacodynamics of Albiglutide

Albiglutide

Type 2 diabetes

BMI 20-45Ph 2Completed30Oct 20121results
NCT02750930Extension to Study 200952 to Evaluate the Long-term Safety, Tolerability and Pharmacodynamics of Albiglutide Liquid Drug Product in Type 2 Diabetes Mellitus Subjects

Albiglutide

Type 2 diabetes

-Ph 4Terminated27Mar 2017-results
NCT01357850A Multi-center, Placebo-controlled Study to Evaluate the Safety of GSK716155 and Its Effects on Myocardial Metabolism, Myocardial Function, and Exercise Capacity in Patients With NYHA Class II/III Congestive Heart Failure

Albiglutide

Cardiovascular disease, Heart failure

EF ≥40%Ph 2Completed15Sep 20121results
NCT00938158A Study of the Pharmacokinetics of Albiglutide in Normal and Renally Impaired Subjects.

Albiglutide

Renal impairment, Type 2 diabetes

HbA1c 6-10.5%Ph 1Completed7Apr 20112
NCT00394030Injection Site Study In Patients With Type 2 Diabetes Mellitus (T2DM) And Healthy Volunteers

Albiglutide

Type 2 diabetes

BMI 25-40Ph 1Completed6Mar 20071
NCT00354536In-patient Study With GSK716155 In Patients With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

-Ph 2Completed5Sep 20061
NCT03015519A Study to Evaluate Pharmacokinetics, Safety and Efficacy of Albiglutide in Pediatric Subjects With Type 2 Diabetes Mellitus

Albiglutide

Type 2 diabetes

HbA1c ≤10%Ph 3Withdrawn3Apr 2020-
NCT02793154An Exploratory Study on the Effects of Repeat Doses of Albiglutide Compared to Exenatide on Gastric Myoelectrical Activity and Gastric Emptying in Type 2 Diabetes Mellitus Subjects

Albiglutide, Exenatide

Type 2 diabetes

BMI 2-35Ph 4Terminated2Mar 2017-results

Showing 1-25 of 41 trials