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Delfa

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Subcutaneous · GLP-2 receptor agonist

Apraglutide

12 trials in this molecule. Source: ClinicalTrials.gov, as of November 5, 2026.

Trials

12

Ongoing

2

Recruiting

1

Completed

8

Sites

220

Countries

26

Endpoints

251

Composite endpoints

7

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Where the program stands

Trials by phase

Phase 1
4
Phase 1/2
3
Phase 2
2
Phase 3
3

Trials by status

Recruiting
1
Active, not recruiting
1
Completed
8
Terminated
1
Withdrawn
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
99
Other (unclassified)
93
Other clinical outcomes
35
Patient-reported / QoL
18
Cardiovascular outcomes
2
Weight & body composition
2
MASH / liver
1
Cardiometabolic biomarkers
1

Top 20 metrics across this asset's endpoints

PGI, changePRO/QoL

5

Treatment-emergent AEs (any)Safety/PK

3

All-cause deathCV

2

Immunogenicity (ADA)Safety/PK

1

Body weight, absolute change (kg)Weight

1

SF-36 totalPRO/QoL

1

EQ-5D indexPRO/QoL

1

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

12 of 12

GLP-1 and incretin trials
Asset / PopulationEligibility highlightEvidence
STARS-2A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)

Apraglutide

Gastrointestinal (gastroparesis / short bowel / pancreatitis)

BMI 18.5-30Ph 3Recruiting94Oct 2028-
STARSTrial to Evaluate Efficacy and Safety of Apraglutide in SBS-IF

Apraglutide

Gastrointestinal (gastroparesis / short bowel / pancreatitis)

-Ph 3Completed68Jan 2024-
STARS extendOpen-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome.

Apraglutide

Gastrointestinal (gastroparesis / short bowel / pancreatitis)

-Ph 3Active, not recruiting66Oct 2027-
NCT05415410Proof-of-concept Trial of Apraglutide in Acute Graft Versus Host Disease (aGVHD)

Apraglutide

-Ph 2Terminated13Dec 2024-results
NCT05706623A Phase 1 Open-Label Evaluation of the Pharmacokinetics and Safety of a Single Dose of Apraglutide in Subjects With Normal and Impaired Hepatic Function

Apraglutide

Hepatic impairment

BMI 18-35Ph 1Completed2Apr 2023-results
STARSnutritionMetabolic Balance Study of Apraglutide in Patients With Short Bowel Syndrome, Intestinal Failure (SBS-IF) and Colon-in-Continuity (CIC)

Apraglutide

Gastrointestinal (gastroparesis / short bowel / pancreatitis)

-Ph 2Completed2Jun 20232results
NCT04699032Study of Pharmacokinetics and Safety of Apraglutide in Participants With Normal and Impaired Kidney Function.

Apraglutide

Chronic kidney disease, Renal impairment

BMI 17.5-40Ph 1Completed2Jul 20211results
NCT03408132Metabolic Balance Study of FE203799 in Patients With SBS With Intestinal Insufficiency

Apraglutide

Gastrointestinal (gastroparesis / short bowel / pancreatitis)

BMI 16-32Ph 1/2Completed1Oct 2019-
NCT05995704Evaluation of Apraglutide on Gastric Emptying

Apraglutide

Healthy volunteers

BMI 18-30Ph 1Completed1Jul 2023-
NCT03415594Safety, Efficacy, PD of FE203799 in Short Bowel Syndrome on Parenteral Support

Apraglutide

Gastrointestinal (gastroparesis / short bowel / pancreatitis)

BMI 16-32Ph 1/2Completed1Nov 20191
NCT06002555Relative Bioavailability of a New Presentation of Apraglutide Versus the Reference Formulation

Apraglutide

Healthy volunteers

BMI 18-35Ph 1Completed1Sep 2023-
NCT03417765Safety, Tolerability, PK/PD of FE 203799 in Adults With Lymphomas

Apraglutide

Oncology

EF ≥50%Ph 1/2Withdrawn0Mar 2019-

Showing 1-12 of 12 trials