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Subcutaneous · Glucagon receptor agonist

Dasiglucagon

24 trials in this molecule. Source: ClinicalTrials.gov, as of November 5, 2026.

Trials

24

Ongoing

0

Recruiting

0

Completed

21

Sites

51

Countries

10

Endpoints

491

Composite endpoints

0

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Where the program stands

Trials by phase

Early Phase 1
1
Phase 1
4
Phase 2
9
Phase 2/3
2
Phase 3
8

Trials by status

Completed
21
Withdrawn
3

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
228
Glycemic / diabetes
148
Other (unclassified)
108
Cardiometabolic biomarkers
4
Patient-reported / QoL
3

Top 20 metrics across this asset's endpoints

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

24 of 24

GLP-1 and incretin trials
Asset / PopulationEligibility highlightEvidence
NCT03941236Extension Trial Evaluating the Long-term Safety and Efficacy of Dasiglucagon in Children With Congenital Hyperinsulinism

Dasiglucagon

Prediabetes / glucose intolerance

Age 5-13Ph 3Completed10Jan 2025-
NCT03777176A Two-Period Open-label Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism

Dasiglucagon

Prediabetes / glucose intolerance

Age 3-12Ph 3Completed10Aug 2020-results
NCT03216226A Trial to Evaluate the Immunogenicity of Dasiglucagon and GlucaGen in Patients With Type 1 Diabetes Mellitus

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

HbA1c ≤10%Ph 3Completed7Feb 2018-results
NCT04172441Trial Evaluating Efficacy and Safety of Dasiglucagon in Children With Congenital Hyperinsulinism

Dasiglucagon

Prediabetes / glucose intolerance

-Ph 2/3Completed6Feb 2022-results
NCT03378635A Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Type 1 Diabetes Subjects

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

HbA1c ≤10%Ph 3Completed5Apr 20181results
NCT03667053Trial to Confirm the Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in T1DM Children

Dasiglucagon

Prediabetes / glucose intolerance

Age 6-17Ph 3Completed5Jun 2019-results
NCT03688711Trial to Confirm the Clinical Efficacy and Safety of Dasiglucagon in the Treatment of Hypoglycemia in Subjects With T1DM

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

HbA1c ≤10%Ph 3Completed3Mar 2019-results
NCT05378672A Study to Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1D

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

Age ≤5Ph 3Completed2Oct 2024-results
NCT03895697A Trial to Compare the Efficacy and Safety of 2 Different Batches of Subcutaneous Dasiglucagon in Patients With T1DM

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

HbA1c ≤10%Ph 3Completed1Jul 2019-
dasiglucagonFeasibility Trial Testing the Bionic Pancreas With ZP4207

Dasiglucagon

Type 1 diabetes

-Ph 2Completed1May 2017-results
NCT02916251ZP4207(Dasiglucagon) Administered to T1D Patients to Assess the PK and PD Compared to Marketed Glucagon

Dasiglucagon

Type 1 diabetes

HbA1c ≤8.5%Ph 2Completed1Apr 2017-
NCT03840278The Bihormonal iLet Bionic Pancreas Feasibility Study

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

-Ph 2/3Completed1Jul 20191results
NCT03735225Evaluation of the Safety, Tolerability and Bioavailability of Dasiglucagon Following Subcutaneous (SC) Compared to IV Administration

Dasiglucagon

Prediabetes / glucose intolerance

Healthy volunteersPh 1Completed1Jun 20191
NCT04764968Pen-Administered Low-Dose Dasiglucagon for Prevention and Treatment of Hypoglycemia in People With Type 1 Diabetes

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

-Ph 2Completed1Dec 20211
NCT04449692Low-dose Dasiglucagon for Prevention of Insulin-Induced Hypoglycemia in People With Type 1 Diabetes

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

HbA1c ≤8%Ph 2Completed1Jan 20211
STABLE-1A Stable Glucagon Analog Administered by a Bihormonal Closed Loop System

Dasiglucagon

Type 1 diabetes

BMI ≤35Ph 2Withdrawn1Dec 2023-
NCT02660008Single Doses of ZP4207 Adm. sc to Hypoglycemic TD1 pt. to Describe the PK and PD of ZP4207 as Comp. to Marketed Glucagon

Dasiglucagon

Prediabetes / glucose intolerance

HbA1c ≤8.5%Ph 2Completed1Jun 20161
NCT03984370Dasiglucagon in the Treatment of Postprandial Hypoglycaemia After Roux-en-Y Gastric Bypass

Dasiglucagon

Prediabetes / glucose intolerance

-Ph 2Completed1Feb 20201
SHERRYTreatment of Post-bariatric Hypoglycaemia

Dasiglucagon

Prediabetes / glucose intolerance

-Ph 2Completed1May 2022-
NCT06588504Research Study in Japan to Compare Dasiglucagon With Glucagon in Treating Very Low Levels of Blood Sugar in Asian Adults With Type 1 Diabetes and Testing of Dasiglucagon for the Same Condition in Japanese Adolescents

Dasiglucagon

Type 1 diabetes

BMI 18.5-29.9Ph 1Completed1Jul 2025-
NCT02390141Multiple Ascending Doses of ZP4207 Administered to HV to Evaluate the Safety, Tolerability, PKs and PDs of ZP4207

Dasiglucagon

Prediabetes / glucose intolerance

Male · Healthy volunteersPh 1Completed1Jul 2015-
NCT02367053Single Ascending Doses of ZP4207 Administered in HV and in T1D to Evaluate Safety, Tolerability PKs and PDs of ZP4207 Compared to a Comparator

Dasiglucagon

Prediabetes / glucose intolerance

HbA1c ≤8.5%Ph 1Completed1Apr 2015-
NCT04192019Micro Glucagon During Exercise in Type 1 Diabetes

Dasiglucagon

Prediabetes / glucose intolerance, Type 1 diabetes

HbA1c ≤8%Early Ph 1Withdrawn0Apr 2024-
NCT04824872Efficacy and Safety of Dasiglucagon for Treatment of Post-bariatric Hypoglycemia in Roux-en-Y Gastric Bypass (RYGB) Operated Adults

Dasiglucagon

Prediabetes / glucose intolerance

BMI ≤40Ph 2Withdrawn0Feb 2023-

Showing 1-24 of 24 trials