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Subcutaneous · GLP-1 agonist

Dulaglutide

140 trials in this molecule. Source: ClinicalTrials.gov, as of July 6, 2026.

Trials

140

Ongoing

29

Recruiting

9

Completed

95

Sites

2,415

Countries

52

Endpoints

2,251

Composite endpoints

182

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Where the program stands

Trials by phase

Phase 1
22
Phase 1/2
2
Phase 2
24
Phase 2/3
2
Phase 3
32
Phase 4
25
Not applicable
33

Trials by status

Not yet recruiting
7
By invitation
3
Recruiting
9
Active, not recruiting
10
Completed
95
Terminated
3
Suspended
1
Unknown
12

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Glycemic / diabetes
671
Safety / tolerability / PK
605
Cardiometabolic biomarkers
231
Weight & body composition
224
Cardiovascular outcomes
138
Other (unclassified)
104
Patient-reported / QoL
95
Other clinical outcomes
81
Renal / kidney
51
MASH / liver
34
Heart failure
17

Top 20 metrics across this asset's endpoints

HbA1c, changeGlycemic

154

Documented hypoglycemiaSafety/PK

104

Body weight, absolute change (kg)Weight

102

Fasting glucose, changeGlycemic

94

HbA1c <7.0% achievementGlycemic

87

AUC₀-∞Safety/PK

74

Heart rate, changeBiomarker

56

Postprandial glucoseGlycemic

55

CmaxSafety/PK

53

Treatment-emergent AEs (any)Safety/PK

49

Expanded / custom MACE compositeCV

44

Immunogenicity (ADA)Safety/PK

38

BMI, changeWeight

33

PancreatitisSafety/PK

31

Thyroid eventSafety/PK

30

HbA1c <6.5% achievementGlycemic

30

HOMA-IR (insulin sensitivity)Glycemic

29

TmaxSafety/PK

23

Total cholesterol, changeBiomarker

16

Triglycerides, changeBiomarker

15

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

140 of 140

GLP-1 and incretin trials
Asset / PopulationEligibility highlightEvidence
SURPASS-CVOTA Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

Dulaglutide, Tirzepatide

Cardiovascular disease, Type 2 diabetes

BMI ≥25 · Established CVDPh 3Completed635Jun 20254
REWINDResearching Cardiovascular Events With a Weekly Incretin in Diabetes (REWIND)

Dulaglutide

Cardiovascular disease, Type 2 diabetes

HbA1c ≤9.5%Ph 3Completed300Aug 201818results
SUSTAIN 7Efficacy and Safety of Semaglutide Versus Dulaglutide as add-on to Metformin in Subjects With Type 2 Diabetes.

Dulaglutide, Semaglutide

Type 2 diabetes

HbA1c 7-10.5%Ph 3Completed209Apr 201713results
AWARD-11A Study of the Efficacy and Safety of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes

Dulaglutide

Type 2 diabetes

BMI ≥25Ph 3Completed208May 20193results
LixiLan-GEfficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination (FRC) Versus GLP-1 Receptor Agonist in Patients With Type 2 Diabetes, With a FRC Extension Period

Albiglutide, Dulaglutide, Exenatide, GLP-1 / incretin class catch-all, Liraglutide, Lixisenatide

Type 2 diabetes

-Ph 3Completed124May 20185results
NCT01191268A Study in Participants With Type 2 Diabetes Mellitus (AWARD-4)

Dulaglutide

Type 2 diabetes

BMI 23-45Ph 3Completed101Feb 20124results
NCT00734474A Study of LY2189265 Compared to Sitagliptin in Participants With Type 2 Diabetes Mellitus on Metformin

Dulaglutide

Type 2 diabetes

BMI 25-40Ph 2/3Completed99Jun 20117results
NCT01126580A Study in Participants With Type 2 Diabetes Mellitus (AWARD-3)

Dulaglutide

Type 2 diabetes

BMI 23-45Ph 3Completed91Nov 20114results
AWARD-1A Study in Participants With Type 2 Diabetes Mellitus

Dulaglutide, Exenatide

Type 2 diabetes

BMI 23-45Ph 3Completed89Nov 20113results
AWARD-7A Study Comparing Dulaglutide With Insulin Glargine on Glycemic Control in Participants With Type 2 Diabetes (T2D) and Moderate or Severe Chronic Kidney Disease (CKD)

Dulaglutide

Chronic kidney disease, Type 2 diabetes

BMI 23-45Ph 3Completed89Jun 20162results
AWARD-2A Study in Participants With Type 2 Diabetes Mellitus (AWARD-2)

Dulaglutide

Type 2 diabetes

BMI 23-45Ph 3Completed78May 20123results
NCT01149421A Study of the Effect of LY2189265 on Blood Pressure and Heart Rate in Type 2 Diabetes

Dulaglutide

Type 2 diabetes

BMI ≥23Ph 2Completed76Sep 20111results
ACHIEVE-PEDSA Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

Dulaglutide, Orforglipron

Obesity / overweight, Type 2 diabetes

HbA1c 6.5-11%Ph 3Not yet recruiting71Mar 2030-
NCT02973100A Study of Investigational Dulaglutide Doses in Participants With Type 2 Diabetes on Metformin Monotherapy

Dulaglutide

Type 2 diabetes

BMI ≥25Ph 2Completed66Jul 2017-results
AWARD-PEDSA Study of Dulaglutide (LY2189265) in Children and Adolescents With Type 2 Diabetes

Dulaglutide

Obesity / overweight, Type 2 diabetes

HbA1c 6.5-11%Ph 3Completed61Jun 20212results
AWARD-6A Study Comparing the Effect of Dulaglutide With Liraglutide in Type 2 Diabetes

Dulaglutide, Liraglutide

Type 2 diabetes

BMI ≤45Ph 3Completed57Nov 20133results
NCT06739122A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

Dulaglutide

Obesity / overweight, Type 2 diabetes

Age 10-17Ph 3Recruiting51Dec 2027-
NCT03131687A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Mellitus

Dulaglutide, Tirzepatide

Type 2 diabetes

BMI 23-50Ph 2Completed49Aug 20184results
NCT00791479Effects of LY2189265 on Glycemic Control in Participants With Type 2 Diabetes

Dulaglutide

Type 2 diabetes

BMI 23-40Ph 2Completed46Jan 20101results
SURPASS J-monoA Study of Tirzepatide (LY3298176) Compared to Dulaglutide in Participants With Type 2 Diabetes

Dulaglutide, Tirzepatide

Type 2 diabetes

BMI ≥23Ph 3Completed46Mar 20216results
AMPLITUDE-DEfficacy and Safety of Efpeglenatide Versus Dulaglutide in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Metformin

Dulaglutide, Efpeglenatide

Type 2 diabetes

-Ph 3Terminated45Oct 2020-results
AWARD-JPNA Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes

Dulaglutide

Type 2 diabetes

BMI ≥18.5Ph 3Completed44Oct 2022-results
NCT05048719A Study of LY3502970 in Participants With Type 2 Diabetes Mellitus

Dulaglutide, Orforglipron

Type 2 diabetes

BMI ≥23Ph 2Completed44Sep 20222results
NCT04867785A Study of LY3437943 in Participants With Type 2 Diabetes

Dulaglutide, Retatrutide

Type 2 diabetes

HbA1c 7-10.5%Ph 2Completed43Jul 20222results
AWARD-10A Study of Dulaglutide (LY2189265) in Participants With Type 2 Diabetes Mellitus

Dulaglutide

Type 2 diabetes

BMI ≤45Ph 3Completed41Feb 20172results

Showing 1-25 of 140 trials