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Subcutaneous · GLP-1 agonist

Efsubaglutide Alfa

14 trials in this molecule. Source: ClinicalTrials.gov, as of November 5, 2026.

Trials

14

Ongoing

6

Recruiting

3

Completed

7

Sites

129

Countries

3

Endpoints

204

Composite endpoints

3

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Where the program stands

Trials by phase

Phase 1
4
Phase 2
4
Phase 2/3
3
Phase 3
1
Phase 4
1
Not applicable
1

Trials by status

Not yet recruiting
2
Recruiting
3
Active, not recruiting
1
Completed
7
Unknown
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Glycemic / diabetes
52
Safety / tolerability / PK
50
Weight & body composition
44
Other (unclassified)
29
Cardiometabolic biomarkers
21
MASH / liver
3
Renal / kidney
2
Other clinical outcomes
2
Patient-reported / QoL
1

Top 20 metrics across this asset's endpoints

AUC₀-∞Safety/PK

5

CmaxSafety/PK

2

Fasting glucose, changeGlycemic

2

TmaxSafety/PK

1

Half-lifeSafety/PK

1

Treatment-emergent AEs (any)Safety/PK

1

Body weight, absolute change (kg)Weight

1

Immunogenicity (ADA)Safety/PK

1

Body weight, % changeWeight

1

Total fat massWeight

1

HbA1c, changeGlycemic

1

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

14 of 14

GLP-1 and incretin trials
Asset / PopulationEligibility highlightEvidence
NCT04998032A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients On Metformin Treatment(SUPER-2)

Efsubaglutide Alfa

Type 2 diabetes

BMI ≤35Ph 2/3Completed61Jun 20233
NCT06921486The Efficacy and Safety of Efsubaglutide Alfa Injection in Overweight and Obese Subjects (ENLIGHT)

Efsubaglutide Alfa

Obesity / overweight

BMI ≥28Ph 2/3Active, not recruiting41Aug 2026-
NCT06849843A Study of 3mg Once Every Two Weeks Administration of Efsubaglutide Alfa Injection in Type 2 Diabetes Patients.

Efsubaglutide Alfa

Type 2 diabetes

BMI ≤40Ph 2Completed10May 2025-
NCT07693426Phase Ib Study of Efsubaglutide Alfa Injection in Obese Adolescents

Efsubaglutide Alfa

Obesity / overweight

Age 12-17Ph 1Recruiting5Apr 2027-
NCT07114419The Efficacy and Safety of Efsubaglutide Alfa in Overweight/Obesity(SPARKLE)

Efsubaglutide Alfa

Obesity / overweight

BMI ≥30Ph 2Recruiting5Jun 2026-
LIGHTA Study of the Efficacy and Safety of Efsubaglutide Alfa in Overweight or Obesity Patients

Efsubaglutide Alfa

Obesity / overweight

BMI ≥28Ph 2Completed3Nov 2024-
NCT04314622A Study of Supaglutide in Chinese Type 2 Diabetes Patients

Efsubaglutide Alfa

Type 2 diabetes

BMI 20-40Ph 2Completed1Oct 20201
NCT05694221Drug Drug Interaction (DDI) Between Supaglutide and Digoxin or Metformin

Efsubaglutide Alfa

Healthy volunteers

BMI 20-28Ph 1Completed1Jun 20231
NCT04994288A Study of Efficacy and Safety of Supaglutide in Type 2 Diabetes Patients(SUPER-1)

Efsubaglutide Alfa

Type 2 diabetes

BMI ≤35Ph 2/3Completed1Jun 20233
NCT06605287The Progress of Diabetes After Supaglutide Treatment in Type 2 Diabetes Patients

Efsubaglutide Alfa

Type 2 diabetes

HbA1c ≤7%-Unknown1Dec 20241
BRIDGE-BRA Bridging Study of Efsubaglutide Alfa in Healthy Adults in Brazil

Efsubaglutide Alfa

Type 2 diabetes

BMI 18-28Ph 1Not yet recruiting1Aug 2026-
NCT07163650Evaluating Anti-Obesity Medications 6 Months After Metabolic Surgery

Efsubaglutide Alfa

Obesity / overweight

BMI ≥28Ph 4Recruiting1Nov 2026-
NCT03745885A Study of the Efficacy and Safety of Supaglutide in Healthy Participants

Efsubaglutide Alfa

Type 2 diabetes

BMI 18-28Ph 1Completed1Jun 20191
NCT06900075Efficacy and Safety of Efsubaglutide Alfa Injection 3 Mg Q2W in T2D Patients

Efsubaglutide Alfa

Type 2 diabetes

BMI 19-35Ph 3Not yet recruiting0Jan 2026-

Showing 1-14 of 14 trials