Skip to main content
Delfa

← All assets

Subcutaneous · GLP-1 / GIP / glucagon triple

UBT251

11 trials in this molecule. Source: ClinicalTrials.gov, as of July 6, 2026.

Trials

11

Ongoing

9

Recruiting

3

Completed

2

Sites

79

Countries

11

Endpoints

125

Composite endpoints

1

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Where the program stands

Trials by phase

Phase 1
2
Phase 2
6
Phase 3
3

Trials by status

Not yet recruiting
6
Recruiting
3
Completed
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Weight & body composition
30
Glycemic / diabetes
27
Cardiometabolic biomarkers
23
MASH / liver
13
Safety / tolerability / PK
12
Other (unclassified)
10
Renal / kidney
7
Patient-reported / QoL
3

Top 20 metrics across this asset's endpoints

HbA1c, changeGlycemic

2

Fasting glucose, changeGlycemic

2

Postprandial glucoseGlycemic

1

Body weight, absolute change (kg)Weight

1

Waist circumference, changeWeight

1

HbA1c <7.0% achievementGlycemic

1

HbA1c <6.5% achievementGlycemic

1

Systolic BP, changeBiomarker

1

Diastolic BP, changeBiomarker

1

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

11 of 11

GLP-1 and incretin trials
Asset / PopulationEligibility highlightEvidence
NCT07668388A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes

Semaglutide, UBT251

Chronic kidney disease, Obesity / overweight, Type 2 diabetes

BMI 25-50Ph 2Not yet recruiting69Oct 2027-
NCT07395687A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity

UBT251

Obesity / overweight

-Ph 2Recruiting3Jan 2027-
NCT07710768A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body Weight

UBT251

Obesity / overweight

BMI 27-39.9Ph 1Not yet recruiting1Apr 2027-
T2DMUBT251 Injection Phase II (Type 2 Diabetes Mellitus) Study

Semaglutide, UBT251

Type 2 diabetes

BMI 23-40Ph 2Completed1Nov 2025-
MASHA Study of UBT251 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)

UBT251

MASH / NAFLD / liver fibrosis

BMI ≥24Ph 2Recruiting1Jun 2027-
NCT07177469UBT251 Injection Phase II Study (Overweight or Obesity)

UBT251

Obesity / overweight

BMI ≥28Ph 2Completed1Oct 2025-
NCT07710729A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become Pregnant

UBT251

Obesity / overweight

BMI 27-39.9Ph 1Not yet recruiting1Apr 2027-
NCT07648225UBT251 Injection Phase Ⅲ Study (Overweight or Obesity)

UBT251

Obesity / overweight

BMI ≥28Ph 3Not yet recruiting1Sep 2027-
NCT07134335UBT251 Injection Phase II Clinical Study (CKD)

UBT251

Chronic kidney disease, Obesity / overweight

BMI ≥24Ph 2Recruiting1Jul 2030-
UNIGUIDE-1Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Diet and Exercise Alone(UNIGUIDE-1)

UBT251

Obesity / overweight, Type 2 diabetes

BMI ≥23Ph 3Not yet recruiting1Sep 2027-
UNIGUIDE-2Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2)

Semaglutide, UBT251

Obesity / overweight, Type 2 diabetes

BMI ≥23Ph 3Not yet recruiting0Feb 2028-

Showing 1-11 of 11 trials