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Subcutaneous · GLP-1 agonist

Zovaglutide

11 trials in this molecule. Source: ClinicalTrials.gov, as of November 5, 2026.

Trials

11

Ongoing

6

Recruiting

0

Completed

5

Sites

65

Countries

2

Endpoints

94

Composite endpoints

0

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Where the program stands

Trials by phase

Phase 1
7
Phase 1/2
1
Phase 2
2
Phase 3
1

Trials by status

Not yet recruiting
2
Active, not recruiting
4
Completed
5

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Safety / tolerability / PK
58
Weight & body composition
18
Other (unclassified)
14
Cardiometabolic biomarkers
2
Glycemic / diabetes
1
Other clinical outcomes
1

Top 20 metrics across this asset's endpoints

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

11 of 11

GLP-1 and incretin trials
Asset / PopulationEligibility highlightEvidence
NCT07230119A Study of Zovaglutide in Subjects With Overweight or Obesity (HORIZON-1)

Zovaglutide

Obesity / overweight

-Ph 3Active, not recruiting45May 2027-
NCT07812597A Study Evaluating Safety and Tolerability of Switching From Semaglutide to Zovaglutide in Adults With Obesity (HORIZON-SWITCH-SZ)

Semaglutide, Zovaglutide

Obesity / overweight

BMI ≥28Ph 2Not yet recruiting16Jan 2028-
NCT07020884A Study of ZT002 Injection With Subjects With Overweight or Obesity

Zovaglutide

Obesity / overweight

BMI ≥28Ph 2Completed16May 2025-
NCT07443059A Study of Zovaglutide (ZT002 Injection) in Participants With Impaired Kidney Function and Healthy Participants

Zovaglutide

Obesity / overweight

BMI 19-32Ph 1Active, not recruiting3Dec 2026-
NCT07916194A Study of Zovaglutide (ZT002 Injection) in Participants With Hepatic Impairment and Healthy Participants

Zovaglutide

Obesity / overweight

BMI 18-32Ph 1Not yet recruiting3Jun 2027-
NCT06423872A SAD Study of ZT002 Injection in Healthy Participants

Zovaglutide

Type 2 diabetes

BMI ≥55Ph 1Completed1Oct 2023-
NCT07065032A Study of ZT002 Injection in Adult Chinese Subjects With Type 2 Diabetes Mellitus (T2DM)

Zovaglutide

Type 2 diabetes

BMI 22-35Ph 1/2Completed1Jul 2024-
NCT07550816Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese Participants

Zovaglutide

Obesity / overweight

BMI 24-35Ph 1Active, not recruiting1Dec 2026-
NCT06371326A Study of ZT002 Injection in Participants With Overweight or Obesity

Zovaglutide

Obesity / overweight

BMI 24-28Ph 1Completed1Apr 2024-
NCT07697846A Study to Investigate the Effects of Zovaglutide (ZT002 Injection) on QTc Interval in Healthy Adults

Zovaglutide

Obesity / overweight

BMI 24-35Ph 1Active, not recruiting1Jan 2027-
NCT05491421A Study of ZT002 in Healthy Participants

Zovaglutide

Type 2 diabetes

-Ph 1Completed1Apr 2023-

Showing 1-11 of 11 trials