Lead sponsor
Novo Nordisk A/S
451 GLP-1 and incretin trials led. Source: ClinicalTrials.gov, as of July 6, 2026.
451
Trials led
64
Ongoing
945,532
Total enrollment
7,776
Sites
Distinct sites across this sponsor's lead trials. A site running several of them counts once, matching the map. Total enrollment sums each trial's reported enrollment, whether planned or actual.
Portfolio
How this sponsor's trials break down
Trials by phase
Phase 1
172
Phase 2
38
Phase 3
150
Phase 4
13
Not applicable
78
Trials by status
Not yet recruiting
15
By invitation
9
Recruiting
23
Active, not recruiting
17
Completed
374
Terminated
4
Withdrawn
8
Unknown
1
Trials led
TrialEligibility highlightPhaseStatusEnrollment
A Master Protocol for Semaglutide Effects on Cardiovascular and Obesity-related Outcomes in People With Overweight or Obesity in the Real World-not applicableCompleted285,327
Epidemiological Assessment of the Risk for Pancreatic Cancer Associated With the Use of Semaglutide in Patients With Type 2 Diabetes - A Cohort Study Based on Nordic Registry Data-not applicableUnknown194,928
Estimation of Malignancy Rates Within Humedica Patient Populations Sampled to be Representative of Liraglutide Initiators and LEADER™ Trial Participants-not applicableCompleted9,999
An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)-not applicableBy invitation6,750
Evaluating the Safety and Effectiveness of Liraglutide in Subjects With Type 2 Diabetes-not applicableCompleted4,121
Effect of Liraglutide on Body Weight in Non-diabetic Obese Subjects or Overweight Subjects With Co-morbidities: SCALE™ - Obesity and Pre-diabetes-Ph 3Completed3,731
Post-Marketing Surveillance (Special Use-results Surveillance) on Long-term Use With Ozempic®-not applicableCompleted3,217
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose WeightBMI ≥35Ph 3Recruiting2,500
Long-Term Effectiveness of Liraglutide for Treatment of Type 2 Diabetes in Daily Practice-not applicableCompleted1,788
A Research Study to Compare Different Versions of Injectable CagriSema and Placebo in People With Excess Body Weight-Ph 3Not yet recruiting1,400
Liraglutide or Insulin in Real Life Usage in Patients With Diabetes Mellitus Type 2-not applicableCompleted1,344
A Study to Evaluate the Safety of Exposure to Wegovy During PregnancyBMI ≥30not applicableBy invitation1,139
Post-marketing Surveillance (Special Use-results Surveillance) on Use With Liraglutide (Victoza®)-not applicableCompleted1,092
Special Use - Results Surveillance on Long-term Use With Wegovy®BMI ≥27not applicableActive, not recruiting1,071
A Retrospective Database Assessment of Clinical Effectiveness in Type 2 Diabetes Patients Treated With Liraglutide From Primary Care Centers in Sweden-not applicableCompleted1,059
A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Tirzepatide in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 InhibitorBMI ≥30Ph 3Completed1,024
The Effect of Insulin Detemir in Combination With Liraglutide and Metformin Compared to Liraglutide and Metformin in Subjects With Type 2 DiabetesHbA1c 7-10%Ph 3Completed987
Investigation of Safety and Efficacy of Once-daily Semaglutide in Obese Subjects Without Diabetes MellitusBMI ≥30Ph 2Completed957
Retrospective Collection of Effectiveness and Safety Data From Patients Treated With Liraglutide or DPP-4 Inhibitor in Primary Care in Europe-not applicableCompleted952
Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 DiabetesBMI ≤45Ph 3Completed929
Effect of Liraglutide on Body Weight in Overweight or Obese Subjects With Type 2 Diabetes: SCALE™ - DiabetesBMI ≥27Ph 3Completed846
A Multicentre, Prospective, Single-arm, Non-interventional Regulatory Post-marketing Surveillance (rPMS) Study to Investigate the Safety and Effectiveness of Wegovy® (Semaglutide) in Patients With Obesity and Patients With Overweight in Routine Clinical Practice in Korea-not applicableBy invitation840
A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose WeightBMI ≥30Ph 3Completed809
A Regulatory Post-marketing Surveillance (rPMS) Study to Evaluate the Safety and Effectiveness of Saxenda®(Liraglutide 3.0 mg) in Obese Patients and Overweight Patients With Obesity-related Comorbidities in Routine Clinical Practice in Korea.-not applicableCompleted758
Regulatory Post Marketing Surveillance (rPMS) Study of Xultophy® (Insulin Degludec/Liraglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea-not applicableCompleted750
A Study to Evaluate Safety of Exposure to Wegovy During PregnancyFemalenot applicableBy invitation728
Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 DiabetesBMI 25-40Ph 2Completed706
Research Study Investigating How Well NNC0174-0833 Works in People Suffering From Overweight or Obesity.-Ph 2Completed706
Research Study on Whether a Combination of 2 Medicines (NNC0194 0499 and Semaglutide) Works in People With Non-alcoholic Steatohepatitis (NASH)-Ph 2Completed698
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes MellitusBMI ≤45Ph 3Completed665
A Trial Comparing the Efficacy and Safety of Liraglutide 1.8 mg/Day to Liraglutide 0.9 mg/Day in Japanese Subjects With Type 2 Diabetes Mellitus.HbA1c 7.5-10%Ph 3Completed635
Multiple Dose Trial Examining Dose Range, Escalation and Efficacy of Oral Semaglutide in Subjects With Type 2 DiabetesHbA1c 7-9.5%Ph 2Completed632
A Study of the Effectiveness of Xultophy® (Insulin Degludec/Liraglutide) in an Adult Real-world Population With Type 2 Diabetes Mellitus-not applicableCompleted611
A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-termBMI ≥30Ph 3Active, not recruiting609
Regulatory Post Marketing Surveillance (rPMS) Study of Ozempic (Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in Korea-not applicableBy invitation600
Regulatory Post Marketing Surveillance (rPMS) Study of Rybelsus (Oral Semaglutide) to Evaluate Safety and Effectiveness in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in KoreaFemalenot applicableNot yet recruiting600
A Research Study to Look Into How Semaglutide, Together With a Lower Dose of Insulin Glargine, Compares to a Higher Dose of Insulin Glargine Alone in People With Type 2 Diabetes (SUSTAIN OPTIMIZE)HbA1c 7-10%Ph 3Completed573
A Research Study Looking at the Comparability of 2 Different Forms of Oral Semaglutide in Healthy PeopleBMI 21-32Ph 1Completed546
A Research Study to See How Semaglutide Helps People With Excess Weight and Type 2 Diabetes Lose WeightBMI ≥30Ph 3Completed512
A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) Versus Basal-bolus Therapy in Subjects With Type 2 Diabetes MellitusHbA1c 7-10%Ph 3Completed506
STEP TEENS Weight Maintenance: A Research Study on How Well Semaglutide Helps Teenagers With Excess Body Weight to Lose Weight and Maintain Weight LossAge 12-15Ph 4Active, not recruiting500
A Research Study Looking at How Well a Combination of the Medicines Semaglutide and NNC0480-0389 Works in People With Type 2 DiabetesBMI ≥25Ph 2Completed500
A Research Study Comparing Wegovy to Other Weight Management Drugs in People Living With Obesity in America-Ph 4Completed500
SEMA-CardioDiab HUNGARY: A Research Study to Understand the Effects of Oral Semaglutide on Blood Sugar Levels, Weight, and Cardiovascular Risk in People With Type 2 Diabetes Patients in HungaryHbA1c ≥7%not applicableRecruiting470
A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease-Ph 2Recruiting465
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight-Ph 3Recruiting460
The Effect of Liraglutide Versus Placebo When Added to Basal Insulin Analogues With or Without Metformin in Subjects With Type 2 DiabetesBMI 20-45Ph 3Completed451
A Research Study Comparing How Well Different Doses of the Medicine NNC0487-0111 Lower Blood Sugar in People With Type 2 DiabetesBMI ≤50Ph 2Completed448
Comparison of Liraglutide Versus Placebo in Weight Loss Maintenance in Obese Subjects: SCALE - MaintenanceBMI 27-30Ph 3Completed422
A Randomised Controlled Clinical Trial in Type 2 Diabetes Comparing Semaglutide to Placebo and LiraglutideHbA1c 7-10%Ph 2Completed415
Research Study Looking at How Well Semaglutide Works in People Suffering From Obesity and Knee OsteoarthritisBMI ≥30Ph 3Completed407
A Research Study to Compare Two Different Versions of Injectable CagriSema in People With Type 2 DiabetesBMI 25-39.9Ph 2Not yet recruiting400
A Research Study to Look Into the Long-term Effect on Weight Loss of CagriSema in People With Obesity-Ph 3Active, not recruiting400
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 DiabetesBMI ≤35Ph 3Completed400
A Research Study to Compare Two Semaglutide Medicines in People With Type 2 DiabetesHbA1c 7-10.5%Ph 3Completed388
A Research Study Looking at New Protein-based Tablets in Healthy Male ParticipantsBMI 20-29.9Ph 1Completed384
Effects of Biphasic Insulin Aspart 70/30 vs. Exenatide in Type 2 Diabetes Patients Not Reaching Blood Glucose Targets on Metformin and a Sulfonylurea.HbA1c ≥8%Ph 3Completed373
The Efficacy and Safety of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin in Chinese Subjects With Type 2 DiabetesHbA1c 7-10%Ph 4Completed368
Safety and Efficacy of Liraglutide in Combination With an OAD in Subjects With Type 2 Diabetes Insufficiently Controlled on OAD AloneBMI ≤40Ph 3Completed363
Effect of Liraglutide in Obese Subjects With Moderate or Severe Obstructive Sleep Apnoea: SCALE™ - Sleep ApnoeaBMI ≥30Ph 3Completed359
A Research Study Looking at Long-term Blood Sugar Control in People With Type 2 Diabetes Being Treated With Xultophy® in a Real-world Setting in ItalyHbA1c ≥3%not applicableCompleted359
A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Help People With Excess Body Weight Lose WeightBMI ≥27Ph 2Completed354
The Effect of Insulin Degludec in Combination With Liraglutide and Metformin in Subjects With Type 2 Diabetes Qualifying for Treatment IntensificationHbA1c 7.5-10%Ph 3Completed346
A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity-Ph 2Recruiting333
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Denmark and Sweden, as Part of Local Clinical Practice (SURE DENMARK/SWEDEN)HbA1c ≤12%not applicableCompleted333
A Research Study to See How Well CagriSema Helps People in East Asia With Excess Body Weight Lose WeightBMI ≥27Ph 3Completed331
In-market Utilisation of Liraglutide Used for Weight Management in Europe-not applicableCompleted316
A Research Study to Understand How People With Type 2 Diabetes Take Ozempic® and if the Ozempic®App Helps Them Stay on This Treatment-not applicableCompleted304
LIRA-ADD2SGLT2i - Liraglutide Versus Placebo as add-on to SGLT2 Inhibitors.HbA1c 7-9.5%Ph 3Completed303
A Research Study to See How Well Different Doses of CagriSema Help People With Excess Body Weight Lose Weight-Ph 3Completed300
Study to Evaluate the Safety and Effectiveness of Saxenda® for Weight Management in Routine Clinical Practice in Taiwan.-not applicableCompleted300
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 DiabetesBMI 25-50Ph 2Not yet recruiting300
A Research Study Comparing How Well Different Doses of the Medicine NN0519-0130 Lower Blood Sugar in People With Type 2 DiabetesHbA1c 7.5-10%Ph 2Completed299
Research Study Comparing New Tablets of Semaglutide in New Doses, in Healthy PeopleBMI 21-29.9Ph 1Completed290
Efficacy and Safety of Liraglutide Versus Placebo as add-on to Existing Diabetes Medication in Subjects With Type 2 Diabetes and Moderate Renal ImpairmentBMI 20-45Ph 3Completed279
A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (C) Semaglutide TabletsBMI 20-29.9Ph 1Completed278
A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (D) Semaglutide TabletsBMI 20-29.9Ph 1Completed274
A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 DiabetesHbA1c 7-10%Ph 2Recruiting270
A Research Study About Weight Loss and Treatment Patterns With the Use of Saxenda® in Adults in Real-life Settings in SwitzerlandBMI ≥35not applicableCompleted269
A Research Study to See if Two Different Formulations of Oral Semaglutide Are Equally Safe and Effective in Reducing the Blood Sugar Level in Japanese People With Type 2 DiabetesHbA1c 7-10.5%Ph 3Active, not recruiting264
Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 DiabetesBMI ≤35Ph 3Completed264
A Research Study to Compare How Much Semaglutide is Found in the Blood With Different Tablets of Oral Semaglutide in Healthy ParticipantsBMI 23-34.9Ph 1Completed264
Efficacy and Safety of Liraglutide in Combination With Insulin Therapy Compared to Insulin Alone in Japanese Subjects With Type 2 DiabetesBMI ≤45Ph 3Completed257
Effect of Liraglutide for Weight Management in Pubertal Adolescent Subjects With ObesityBMI ≥30Ph 3Completed251
A Research Study to Look Into How Well Semaglutide Medicine Works at Different Doses in People With Type 2 Diabetes and OverweightBMI ≥27Ph 2Completed245
A Research Study to Compare Blood Levels of Cagrilintide After Multiple Doses of Different Versions of Cagrilintide in Adults With Overweight or ObesityBMI 27-34.9Ph 1Not yet recruiting234
A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity-Ph 2Not yet recruiting230
Effect of Liraglutide on Blood Glucose Control in Japanese Subjects With Type 2 DiabetesBMI ≤30Ph 2Completed226
Efficacy and Safety of Metformin and Liraglutide in Obese Subjects With Type 2 Diabetes Previously Treated With an Oral Hypoglycemic AgentBMI 27-42Ph 2Completed223
A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Switzerland, as Part of Local Clinical Practice (SURE SWITZERLAND)HbA1c ≤12%not applicableCompleted215
A Research Study on How Well Semaglutide Works in Adolescents With Overweight or ObesityHbA1c ≤10%Ph 3Completed201
Real World Effectiveness of Combining an Employer-based Weight Management Program With Medication for Chronic Weight Management in Employees With Obesity-Ph 4Completed200
Comparison of Liraglutide and Glimepiride on Blood Sugar Control in Subjects With Type 2 DiabetesHbA1c 7.5-10%Ph 2Completed196
Investigating Safety, Tolerability, PK and PD for Multiple Doses of NNC9204-0530 in Combination With Liraglutide in Male and Female Subjects Being Overweight or With ObesityBMI 25-39.9Ph 1Completed187
A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Mexico, as Part of Local Clinical Practice-not applicableCompleted187
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 DiabetesHbA1c ≤10%Ph 2Completed177
Investigation on Safety, Tolerability and Pharmacokinetics of Single and Multiple Doses of a Long-acting GLP-1 Analogue (Semaglutide) in an Oral Formulation in Healthy Male SubjectsBMI 20-30Ph 1Completed170
A Thorough QTc Evaluation of the Effect of Semaglutide on Cardiac Repolarisation in Healthy SubjectsBMI 20-30Ph 1Completed168
A Study of How CagriSema Works on Appetite in People With Excess Body WeightBMI 18.5-24.9Ph 1Completed164
Investigate Safety, Tolerability and Pharmacokinetics for Single Doses of NNC9204-0530 Alone and in Combination With Liraglutide in Overweight to Obese But Otherwise Healthy Male SubjectsBMI 27-35Ph 1Completed163
A Research Study of a New Medicine NNC0519-0130 in Healthy People, People With High Body Weight and People With Type 2 Diabetes.Healthy volunteersPh 1Completed161
Investigation of Optimal Dosing Conditions for a Long Acting GLP-1 Analogue in Healthy Male SubjectsBMI 18.5-30Ph 1Completed161
Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 DiabetesBMI 25-45 · Established CVDPh 1Completed158
A Clinical Trial Comparing Semaglutide in Healthy People Who Eat and Take the Medicine at Different TimesBMI 20-29.9Ph 1Completed156
First Research Study to Look at How Two Medicines, NNC0480-0389 and Semaglutide, Work Together in Healthy People, in People With High Body Weight and in People With DiabetesBMI 20-29.9Ph 1Completed152
A Research Study Investigating How Semaglutide and Dapagliflozin Act in Your Body When Dosed in One TabletBMI 20-29.9Ph 1Completed152
Research Study Investigating How Well Semaglutide Works in People From Thailand and South Korea Living With ObesityBMI ≥25Ph 3Completed150
A Research Study to See How a New Weekly Insulin, Insulin Icodec When Given Along With Semaglutide Helps in Reducing the Blood Sugar Level in Patients With Type 2 DiabetesHbA1c 7.5-10.5%Ph 3Completed148
Effect of Liraglutide as add-on to Metformin Compared to Either Liraglutide or Metformin Alone, or to a Combination of Metformin and a SU (Sulphonylurea) Agent in Subjects With Type 2 DiabetesBMI 25-40Ph 2Completed145
A Research Study on How NNC0487-0111 Works in People With Overweight or ObesityBMI 25-34.9Ph 1Completed144
A Research Study to Investigate the Effects of CagriSema Compared to Placebo in People With Type 2 Diabetes and Painful Diabetic Peripheral NeuropathyBMI ≥25Ph 2Active, not recruiting142
A Research Study Comparing Different Ways of Increasing the Dose of NNC0519-0130 in Participants With Overweight or ObesityBMI 27-44.9Ph 1Completed134
A Research Study Looking at Different Oral Formulations and the Effect of Food Intake on How the Medicine NNC0487-0111 Behaves in the Body of Participants Living With Overweight or ObesityBMI 27-39.9Ph 1Completed133
A Research Study to See How a New Medicine (NNC0487-0111) Works in People With Overweight or Obesity When Injected Under the SkinBMI 27-39.9Ph 2Completed125
Evaluation of Optimal Dosing Conditions for GLP-1 Analogue NNC0113-0987 When Administered Orally in Healthy Male SubjectsBMI 18.5-29.9Ph 1Completed122
A Research Study Comparing the Effect of Different Dosing Conditions on Blood Levels of Semaglutide in a New Tablet Composition in Healthy ParticipantsBMI 18.5-29.9Ph 1Completed121
A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation IIIBMI 22-31.9Ph 1Completed121
A Research Study Looking at How NNC0487-0111 Affects Food Intake, Appetite and Metabolism After Meals in People With Obesity-Ph 1Recruiting120
A Research Study Looking Into How Cagrilintide Influences Food Intake and Appetite in People With Overweight or Obesity-Ph 1Recruiting120
A Research Study to Investigate How Well NNC0165-1875 in Combination With Semaglutide Works in People With ObesityBMI 30-45Ph 2Completed120
Evaluation of the Tolerability of Cagrilintide in Participants Not Tolerating GLP-1-RA Therapies Due to Gastrointestinal Adverse Events-Ph 1Not yet recruiting114
Comparing Semaglutide Administered Subcutaneously Once Daily to Semaglutide Administered Subcutaneously Once WeeklyBMI 20-29.9Ph 1Completed113
A Research Study to Compare Two Different Forms of Once-weekly Semaglutide in Two Different Injection PensBMI 25-34.9Ph 1Completed111
A Study of Once-Daily NNC0090-2746 in Participants With Type 2 Diabetes Inadequately Controlled With Metformin-Ph 2Completed108
Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of a Long-acting GLP-1 Analogue in Healthy Male Subjects and Male Subjects With Type 2 DiabetesBMI ≤30Ph 1Completed107
A Research Study Looking at How Cagrilintide Works on the Heart Rhythm in Healthy ParticipantsBMI 23-29.9Ph 1Completed107
In Market Utilisation of Liraglutide Used for Weight Management in the UK: a Study in the CPRD Primary Care Database-not applicableCompleted105
Research Study Comparing Different Tablets With the Study Medicine Semaglutide in Healthy MenBMI 20-29.9Ph 1Completed105
Safety Study of Weekly Semaglutide in Chilean Participants With Type 2 DiabetesHbA1c 7.5-10%Ph 4Completed104
A Study Comparing the Injection Site Pain Experience After the Injection of Semaglutide B and Semaglutide D With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and ObesityBMI ≥25Ph 2Completed104
Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide scBMI ≥25Ph 4Completed104
A Study Comparing the Injection Site Pain Experience After the Injection of 2 Different Solutions of Semaglutide With 2 Different Injection Pens, a Compound for the Treatment of Type 2 Diabetes and ObesityBMI ≥25Ph 2Completed103
A Research Study of How Semaglutide Works in People With Disease Affecting the Heart and/or Blood Vessels and Type 2 DiabetesBMI ≤39.9 · Established CVDPh 1Completed101
A Study Looking at How Weekly Injections of Two Hormones - GIP and Amylin - Affect Stomach-related Side Effects in People Who Are Overweight or ObeseFemalePh 1Recruiting100
Investigation of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Dosing of NNC0174-0833 in Subjects With Obesity or OverweightBMI 25-39.9Ph 1Completed96
A Research Study of How NNC0174-0833 Taken With Semaglutide Works in People Who Are Overweight or ObeseBMI 27-39.9Ph 1Completed96
Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NN9924 in Healthy Male SubjectsBMI 21-30Ph 1Completed96
A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 DiabetesBMI 22-35Ph 1Active, not recruiting96
Research Study to Look at How Well Cagrilintide Together With Semaglutide Works in People With Type 2 DiabetesBMI ≥27Ph 2Completed92
A Research Study Looking at New Protein-based Tablets in Healthy Men - Oral Formulation IVBMI 22-31.9Ph 1Completed90
A Research Study of NNC0165-1875 Alone or Together With Semaglutide in People Who Are Overweight or ObeseBMI 25-34.9Ph 1Completed88
A Trial Investigating the Effects of Semaglutide on ß-cell Function in Subjects With Type 2 DiabetesBMI 20-35Ph 1Completed87
Safety, Tolerability, and Profile of Action of Drug in the Body of NN9535 in Healthy Male Japanese and Caucasian SubjectsBMI 18.5-24.9Ph 1Completed84
Investigation on Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Doses of a Long Acting GLP-1 Analogue (NNC0113-0987) in Healthy Male SubjectsBMI 20-29.9Ph 1Completed82
A Study to See How Metabolism is Influenced by Weight Loss Due to Intervention With Cagrilintide and Semaglutide Compared to Diet-Ph 1Recruiting80
Investigating How NNC0487-0111 Regulates Insulin of Adults With Type 2 DiabetesHbA1c 6.5-9.5%Ph 1Recruiting80
SCALE KIDS: Research Study to Look at How Well a New Medicine is at Lowering Weight in Children With ObesityAge 6-12Ph 3Active, not recruiting78
Effect of Food on the Pharmacokinetics of Oral Semaglutide in Healthy SubjectsBMI 18.5-29.9Ph 1Completed78
Efficacy Evaluation of Different Medication Combination in Type 2 Diabetes TreatmentBMI ≤40Ph 4Completed75
A Research Study to Look at How Semaglutide Affects Gastric Emptying in People With ObesityBMI 30-45Ph 1Completed72
A Research Study on How Semaglutide Works in People With Fatty Liver Disease and Liver DamageBMI ≥27Ph 2Completed71
Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal FunctionBMI 18.5-40Ph 1Completed71
Effect of Liraglutide on Gastrointestinal Absorption of Several Drugs and Potential Influence of Liraglutide on Intragastric pHBMI 18-30Ph 1Completed70
A Research Study Looking at the Comparability (Bioequivalence) of Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or ObesityBMI 27-34.9Ph 1Completed68
A Research Study to Look at Similarity Between Semaglutide Versions in Different Injection ToolsBMI 20-29.9Ph 1Completed68
A Research Study Looking at Similarity Between Once-weekly Semaglutide Versions for Different Injection PensBMI 25-34.9Ph 1Completed68
A Study on How Semaglutide Works on Early Stages of Scar Tissue in the Liver Assessed by Pictures of the LiverBMI 25-40Ph 1Completed67
A Research Study of How NNC0174-0833 Behaves in Japanese and Caucasian Volunteers Who Are Normal Weight, Overweight or With ObesityBMI 20-39.9Ph 1Completed66
Investigating the Safety Profile of Liraglutide Under Normal Conditions of Use in Korean Subjects With Type 2 Diabetes Mellitus-not applicableCompleted64
A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or ObesityBMI 25-34.9Ph 1Active, not recruiting63
A Research Study to Look at How CagriSema Influences Food Intake, Appetite and Emptying of the Stomach in People With Excess Body WeightBMI ≥27Ph 1Completed62
A Research Study Looking at How 50 mg Semaglutide Daily Affects Food Intake and Emptying of the Stomach in People With ObesityBMI 30-45Ph 1Completed60
Dose Escalation Trial of Single Subcutaneous Doses of NNC 0113-0217 to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Male SubjectsBMI ≤35Ph 1Completed58
A Research Study Looking at a New Study Medicine (NNC0194-0499) for Weight Control in People With Overweight or ObesityBMI 27-39.9Ph 1Completed57
Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi SyndromeBMI ≥30Ph 3Completed56
Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Hepatic ImpairmentBMI 18.5-40Ph 1Completed56
First Human Dose Trial Investigating Safety, Tolerability and Pharmacokinetics of NNC0194-0499 in Male Subjects With Overweight or ObesityBMI 25-34.9Ph 1Completed56
Investigation of the Effect of Upper Gastrointestinal Disease on the Pharmacokinetics of Oral Semaglutide in Subjects With Type 2 Diabetes.BMI 18.5-39.9Ph 1Completed55
Investigating the Influence of Omeprazole on the Pharmacokinetics of Oral Semaglutide in Healthy SubjectsBMI 18.5-29.9Ph 1Completed54
Investigation on Safety, Tolerability and Pharmacokinetics of Single Doses of NNC0174-0833 in Normal Weight, Overweight to Obese But Otherwise Healthy Male SubjectsBMI 20-35Ph 1Completed54
A Trial to Compare Blood Concentration Levels of Semaglutide Following Subcutaneous Injections of Semaglutide 1 mg by 2 Different Devices (the DV3372 Device and by the PDS290 Semaglutide Pen-injector)BMI 20-29.9Ph 1Completed54
A Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combination Formulation Versus Two Separate FormulationsBMI ≥25Ph 1Completed53
A Trial Investigating the Influence of Oral Semaglutide on the Pharmacokinetics of Lisinopril and Warfarin in Healthy SubjectsBMI 20-29.9Ph 1Completed52
A Trial to Assess the Effects of Liraglutide on Gallbladder Emptying in Overweight and Obese Subjects.BMI ≥27Ph 1Completed52
A Research Study to Compare Blood Levels of Two Different Versions of Cagrilintide in Adults With Excess Body WeightBMI 27-34.9Ph 1Not yet recruiting50
A Trial to Demonstrate Bioequivalence Between Two Insulin Degludec/Liraglutide Formulations, B5 and V2 in Healthy SubjectsBMI 18.5-27Ph 1Completed50
The Effect of Liraglutide on Endothelial Function in Subjects With Type 2 Diabetes MellitusBMI ≤40Ph 3Completed49
A Trial to Assess the Effect of Liraglutide on Gastric Emptying in Healthy Obese VolunteersBMI 30-40Ph 1Completed49
A Trial to Assess the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Oral Semaglutide in Healthy Male Japanese and Caucasian SubjectsBMI 20-25Ph 1Completed48
A Research Study Looking Into the Effect of NNC0519-0130 on Blood Levels of a Birth Control Pill and Emptying of the Stomach in Women After MenopauseBMI 27-39.9Ph 1Completed47
The Effect of Liraglutide Adjunct to Insulin on Glucagon Response to Hypoglycaemia in Subjects With Type 1 DiabetesBMI 20-28Ph 1Completed45
A Trial Investigating the Influence of Oral Semaglutide on the Pharmacokinetics of Levothyroxine and the Influence of Co-administered Tablets on the Pharmacokinetics of Semaglutide Administered Orally in Healthy Subjects.BMI 20-29.9Ph 1Completed45
Investigating the Pharmacokinetics, Safety and Tolerability After a Single Subcutaneous Injection of Semaglutide in Subjects With Mild, Moderate or Severe Hepatic Impairment Compared to Subjects With Normal Hepatic FunctionBMI 18.5-40Ph 1Completed44
A Trial to Assess the Pharmacokinetics, Pharmacodynamics, and the Safety and Tolerability of Semaglutide in Healthy Male Japanese and Caucasian SubjectsBMI 20-25Ph 1Completed44
A Clinical Trial Investigating the Comparison of Three Different Concentrations of NN9535 in Healthy Male SubjectsBMI 18-27Ph 1Completed44
A Research Study on How UBT251 Affects Levels of Midazolam, Caffeine and Warfarin in the Blood of Participants With Excess Body WeightBMI 27-39.9Ph 1Not yet recruiting44
Effect of Liraglutide Compared to Glimepiride on Appetite in Subjects With Type 2 DiabetesBMI 27-40Ph 1Completed43
Effect of Oral Contraceptives After Administration of Semaglutide in Subjects With Type 2 DiabetesBMI 18.5-35Ph 1Completed43
A Research Study Looking at How the Compound NNC0487-0111 Works With Birth Control Pills and Affects Emptying of the Stomach in Women Not Able to Become PregnantBMI 25-39.9Ph 1Completed43
A Research Study Looking at How the Medicine NNC0194-0499 Behaves in Japanese and Non-Asian MenBMI 23-34.9Ph 1Completed42
A Research Study Looking Into Blood Levels of the Medicine NNC0480-0389 in Participants With Reduced Kidney Function Compared to Participants With Normal Kidney FunctionBMI 20-39.9Ph 1Completed42
A Research Study Looking Into Blood and Urine Levels of the Medicine NNC0194-0499 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney FunctionBMI 18.5-39.9Ph 1Completed42
A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney FunctionBMI 20-39.9Ph 1Completed42
Investigating the Pharmacokinetics of Subcutaneous Injections With 1 mg/mL, 3 mg/mL, and 10 mg/mL Semaglutide Strengths and the Absolute Bioavailability of SemaglutideBMI 20-30Ph 1Completed42
A Trial Investigating the Effect of Oral Semaglutide on the Pharmacokinetics of Furosemide and Rosuvastatin in Healthy SubjectsBMI 20-29.9Ph 1Completed41
A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Combined Versus Separate Injections in People With Overweight or ObesityBMI 27-39.9Ph 1Completed40
First Research Study of the Possible New Medicine NNC0113-2023 in Healthy Men.BMI 20-29.9Ph 1Completed40
A Research Study Looking Into How UBT251 Works With Birth Control Tablets and Emptying of the Stomach in Women With Excess Body Weight Not Able to Become PregnantBMI 27-39.9Ph 1Not yet recruiting40
A Trial Investigating the Effect of Semaglutide on Hypoglycaemic Counterregulation Compared to Placebo in Subjects With Type 2 DiabetesBMI 20-35Ph 1Completed38
A Research Study of NNC0165-1562 and Semaglutide in People Who Are Overweight or ObeseBMI 27-39.9Ph 1Completed37
To Investigate the Blood Concentration of Liraglutide as Well as the Effects on Glucose and Insulin After 21 Days of Daily Subcutaneous Injections of Liraglutide or PlaceboBMI 19-27Ph 1Completed37
A Trial to Assess the Pharmacokinetics, Safety and Tolerability of Semaglutide in Healthy Chinese SubjectsBMI 20-24.9Ph 1Completed36
A Research Study of How a New Medicine Called Amycretin, Given as Tablets, Works in Japanese Men With ObesityBMI 25-34.9Ph 1Completed36
A Research Study Looking Into Blood Levels of the Medicine NNC0519-0130 in the Body in Participants With Normal or Reduced Kidney FunctionBMI 20-39.9Ph 1Completed36
A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants When Injected Under the Skin.BMI 24-34.9Ph 1Completed36
A Research Study Looking Into Blood Levels of the Medicine NNC0487-0111 in the Body and How Well it is Tolerated in People With Reduced Liver Function and Normal Liver Function-Ph 1Not yet recruiting35
Effect of Liraglutide on Weight and Appetite in Obese Subjects With Type 2 DiabetesBMI ≥27Ph 2Completed35
A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children.BMI 18.5-29.9Ph 1Completed34
A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body WeightBMI 27-39.9Ph 1Completed34
A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver FunctionBMI 18.5-39.9Ph 1Completed33
A Research Study Looking Into Blood Levels of NNC0174-0833 in People With Normal and Impaired Kidney Function-Ph 1Completed33
Examination of the Effects of Liraglutide on the Mode of Action of Insulin DetemirBMI ≤45Ph 1Completed33
A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Works in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function and How Cagrilintide is Absorbed and Used by the BodyBMI 18.5-39.9Ph 1Completed32
Comparison of the Effect of Liraglutide in Young Versus Elderly Healthy VolunteersBMI 18-30Ph 1Completed32
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Healthy Japanese VolunteersBMI 18-27Ph 1Completed32
Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Metformin and Digoxin in Healthy SubjectsBMI 20-29.9Ph 1Completed32
A Research Study of How Oral Semaglutide Tablets Work in Healthy People Who Are ChineseBMI 20-24.9Ph 1Completed32
Comparison of Liraglutide Inhaled Into the Lungs Compared to Liraglutide Injected Under the Skin in Healthy Male VolunteersBMI 20-30Ph 1Completed32
Safety, Tolerability and Pharmacokinetics of Liraglutide-depot in Healthy SubjectsBMI 20-35Ph 1Completed31
Investigating the Influence of Semaglutide on the Pharmacokinetics of Single Doses of Atorvastatin and Digoxin in Healthy SubjectsBMI 20-29.9Ph 1Completed31
Research Study to Investigate the Effect of NNC0174-0833 on a Birth Control Pill in Women Who Are Not Able to Become PregnantBMI 25-39.9Ph 1Completed31
Safety and Tolerability of Liraglutide in Subjects With Impaired Kidney Function and in Subjects With Normal Kidney Function-Ph 1Completed30
Trial Investigating the Effect of Semaglutide on Energy Intake, Appetite Sensations, Postprandial Glucose and Triglyceride Metabolism and Gastric Emptying in Obese Subjects Compared With PlaceboBMI 30-45Ph 1Completed30
A Research Study to Look at How Insulin 287 and Semaglutide Work in the Body of People With Type 2 Diabetes When Taken Alone or TogetherHbA1c 6-8.5%Ph 1Completed30
A Research Study to Compare Two Forms of Semaglutide in Two Different Pen-injectors in People With Overweight or ObesityBMI 27-34.9Ph 1Terminated29
A Research Study on How NNC0487-0111, a New Medicine, Works in Chinese Participants After 10 Days of Oral DosingBMI 24-34.9Ph 1Completed29
A Research Study Looking at the Comparability (Bioequivalence) of Two Versions of SemaglutideBMI 20-27Ph 1Completed28
A Randomised, Single Centre, Double-blind, Two-period, Cross-over Trial in Healthy Subjects Investigating the Bioequivalence Between Subcutaneous Injections of Semaglutide Produced by Two Manufacturing ProcessesBMI 18.5-30Ph 1Completed28
Timely Detection of Treatment Emergent Serious and Non-serious Adverse Events for Saxenda® in Mexican PatientsBMI ≥30not applicableCompleted27
A Research Study Looking Into the Effect of Semaglutide and NNC0480 0389 on Blood Levels of a Birth Control Pill in Woman After MenopauseBMI 20-29.9Ph 1Completed27
A Trial Investigating the Influence of Oral Semaglutide on Pharmacokinetics of Ethinylestradiol and Levonorgestrel in an Oral Contraceptive Combination Drug in Healthy Postmenopausal FemalesBMI 20-29.9Ph 1Completed25
A Trial to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Liraglutide in Obese Children Aged 7 to 11 YearsAge 7-11Ph 1Completed24
Safety and Tolerability of Liraglutide in Healthy Volunteers and Subjects With Type 2 DiabetesBMI 19-30Ph 1Completed24
Safety of Liraglutide in Subjects With Liver Impairment and in Subjects With Normal Liver FunctionBMI 18.5-40Ph 1Completed24
Influence of Semaglutide on Pharmacokinetics and Pharmacodynamics of Warfarin and Pharmacokinetics of Metformin in Healthy SubjectsBMI 23-30Ph 1Completed24
Investigating Bioequivalence Between Single-dose Liraglutide Administered Subcutaneously With Two Different Pen-injectorsBMI ≥27Ph 1Completed24
A Research Study of How NNC0174-0833 Behaves in Chinese Volunteers Who Are Normal Weight, Overweight or With ObesityBMI 20-39.9Ph 1Completed24
Safety and Tolerability of Insulin Degludec/Liraglutide (A3) in Healthy SubjectsBMI 20-27Ph 1Completed24
A Trial to Investigate the Single Dose Pharmacokinetics of Insulin Degludec/Liraglutide Compared With Insulin Degludec and Liraglutide in Healthy Chinese SubjectsBMI 19-24Ph 1Completed24
A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Japanese MenBMI 20-24.9Ph 1Completed24
A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Chinese MenBMI 20-27.9Ph 1Completed24
A Research Study Looking at How a Single Dose of the Medicine NNC0194-0499 Behaves in Chinese MenBMI 23-34.9Ph 1Completed24
A Research Study Looking at the Effect of Semaglutide on the Immune System and Other Biological Processes in People With Alzheimer's Disease-Ph 3Completed23
Influence on the Effect of an Oral Contraceptive Drug After Administration of Liraglutide in Postmenopausal WomenBMI 18-30Ph 1Completed21
Comparison of Liraglutide Injected at Three Different Injection Sites in Healthy VolunteersBMI 18.5-27.5Ph 1Completed21
A Randomised, Double-blind, Placebo-controlled Trial to Assess Safety, Tolerability and Pharmacokinetics of Liraglutide in Obese Adolescent Subjects Aged 12 to 17 YearsAge 12-17Ph 1Completed21
A Trial Investigating the Effect of Probenecid and Ciclosporin on the Concentrations of SNAC in Healthy SubjectsBMI 18.5-29.9Ph 1Completed21
A Trial to Assess the Effect of Liraglutide on Blood Triglyceride (Fat) Levels After a Meal in Type 2 DiabeticsBMI 18.5-40Ph 1Completed20
Effect of Liraglutide on the Beta-cell Responsiveness in Subjects With Type 2 Diabetes Compared to a Healthy Control GroupBMI 24-35Ph 1Completed20
A Research Study to Look at How Insulin Icodec and Semaglutide Work in the Body of People From China With Type 2 Diabetes When Given Alone or TogetherBMI 18.5-34.9Ph 1Completed20
A Research Study of the New Medicine NNC0519-0130 in Male Chinese Participants Living With Excess Body WeightBMI 24-39.9Ph 1Completed20
A Research Trial Looking at the Comparability of 2 Different Concentrations of Semaglutide for the 0.5 Milligram (mg) DoseBMI 20-29.9Ph 1Completed20
Effect of Liraglutide on Absorption of Paracetamol in Subjects With Type 2 DiabetesBMI 18.5-40Ph 1Completed18
A Research Study to Compare Blood Levels of Cagrilintide and Semaglutide After Single Doses of Different Versions of Injectable CagriSema in Adults With Overweight or ObesityBMI 27-39.9Ph 1Completed18
A Clinical Trial Looking at the Comparability of 2 Different Forms of SemaglutideBMI 25-34.9Ph 1Completed18
Effect of Liraglutide on Glucose Profiles and Gastric Emptying in Subjects With Type 2 Diabetes-Ph 2Completed17
A Research Study Looking Into Blood Levels of Semaglutide and NNC0480-0389 When Given in the Same Injection or in Two Separate Injections in Healthy PeopleBMI 20-29.9Ph 1Completed16
Safety and Tolerability of Liraglutide in Japanese Subjects With Type 2 DiabetesBMI 18.5-30Ph 1Completed15
A Trial Investigating the Effect of Oral Semaglutide Compared With Placebo on Postprandial Glucose and Triglyceride Metabolism, Energy Intake, Appetite Sensations and Gastric Emptying in Subjects With Type 2 DiabetesBMI 20-38Ph 1Completed15
A Research Study to See How Much Semaglutide and SNAC is in the Milk of Healthy, Breastfeeding Women Taking Semaglutide TabletsBMI 20-32.4Ph 1Completed14
Effect of Liraglutide on Pulsatile Insulin Secretion in Subjects With Type 2 DiabetesBMI 24-35Ph 1Completed11
Trial Investigating the Absorption, Metabolism and Excretion After a Single Subcutaneous Dose of [3H]-Semaglutide in Healthy Male SubjectsBMI 20-30Ph 1Completed7
Efficacy and Safety of Liraglutide in Subjects With Type 1 Diabetes Undergoing Islet Cell Transplantation-Ph 2Terminated3
Research Study to Compare Semaglutide Tablets With Empagliflozin or Metformin Tablets in People With Type 2 DiabetesBMI ≥25Ph 3Withdrawnnot disclosed
Non-interventional, Post Marketing Surveillance Study of Xultophy™ (Insulin Degludec/Liraglutide) to Evaluate Long Term Safety and Efficacy in Patients With Type 2 Diabetes Mellitus in Routine Clinical Practice in India-not applicableWithdrawnnot disclosed
A Research Study in Italy to Understand How the Dose Check App Used With Xultophy® Works in the Treatment of People Living With Type 2 DiabetesHbA1c ≤12%not applicableWithdrawnnot disclosed