CompletedPhase NA

The Influence of Acute Moderate-intensity Continuous Exercise on Appetite Regulation

Lead sponsor

Loughborough University

Asset

GLP-1 / incretin class catch-all

Listed sites

Recruiting sites

Actual enrollment

Study population

Healthy volunteers

Eligibility highlights

•BMI 18.5-24.9

Primary endpoints

•Oxyntomodulin•Growth Differentiation Factor 15

Registered trial locations

Locations reported to ClinicalTrials.gov for this trial snapshot. Site count is not enrollment count; per-site enrollment is not available from source.

Identifiers

Registered as

NCT IDNCT06296511

Org study IDLoughborough University

Timeline

Milestones

Study start2023-06-23actual

Primary completion2023-11-07actual

Study completion2023-11-07actual

Study first posted2024-03-06actual

Last update posted2024-03-06actual

Assets

Investigational agents

GLP-1 / incretin class catch-all

Who this study enrolls

Healthy volunteers

Who can enroll

Minimum age18 Years

Maximum age40 Years

SexAll

Healthy volunteersAccepted

Inclusion criteria

•Body mass index between 18.5-24.9 kg/m²;

•Habitually consume three meals a day;

•Able to run continuously for 1 hour;

•Not currently dieting and weight stable for 3 months (< 3 kg change in weight);

•No severe dislike or allergy to any of the study food;

•Regular menstrual cycle in the past 6 months.

Exclusion criteria

•Smokers (vaping is considered smoking in this study);

•Individuals with medical conditions (e.g., diabetes, heart condition);

•Individuals taking medications that may influence the study outcomes;

•Individuals with clinically diagnosed eating disorders.

Endpoints (4)

What's being measured

Protocol endpoints and posted registry outcome measures, grouped into outcome categories. Composite endpoints show their component event types. Standard codes (LOINC, SNOMED CT) are shown where available.

Coverage by outcome category

Other (unclassified)

Patient-reported / QoL

1 endpoint

Secondary/protocol endpoint

Visual analogue score (VAS) for subjective appetite

Time frame:VAS was measured at 0 (baseline), 60, 90, 120, 150, 180, 210 minutes in each trial.

change from baseline, improvement

Other (unclassified)

3 endpoints

Primary/protocol endpoint/low confidence

Oxyntomodulin

Time frame:Blood samples were collected for oxyntomodulin measurements at 0 (baseline), 60, 90, 120, 150, 180, 210 minutes in each trial.

concentration, descriptive

Primary/protocol endpoint/low confidence

Growth Differentiation Factor 15

Time frame:Blood samples were collected for GDF-15 measurements at 0 (baseline), 60, 90, 120, 150, 180, 210 minutes in each trial.

concentration, descriptive

Secondary/protocol endpoint

Energy intake

Time frame:Ad libitum pasta meal provided at 120 minutes.

descriptive

Publications (1)

Bibliography

Records linked to this trial through ClinicalTrials.gov references, PubMed NCT search, and curated study seeds. 'Canonical' marks design/result papers; others are registry references or candidates.

Registry references + supporting bibliography

Effects of acute moderate-intensity continuous running on circulating oxyntomodulin concentrations in healthy men and women.
Appetite2026 Jul 1PMID41833829doi:10.1016/j.appet.2026.108541via clinicaltrials gov reference derived + pubmed nct search

Provenance

Sources

Trial identity, design, statusClinicalTrials.gov API v2

Snapshot dateJuly 6, 2026

Endpoint classificationDelfa endpoint taxonomy v2 (May 13, 2026)

Results tableno registry results posted yet

Trial facts come from public ClinicalTrials.gov records. Endpoint categories are Delfa's classification of those records, not a ClinicalTrials.gov field. All figures reflect the July 6, 2026 snapshot.