Lead sponsor
Merck Sharp & Dohme LLC
15 GLP-1 and incretin trials led. Source: ClinicalTrials.gov, as of July 1, 2026.
15
Trials led
1
Active
1,873
Total enrollment
251
Sites
Distinct sites across this sponsor's lead trials. A site running several of them counts once, matching the map. Total enrollment sums each trial's reported enrollment, whether planned or actual.
Portfolio
How this sponsor's trials break down
Trials by phase
Phase 1
9
Phase 2
5
Phase 3
1
Trials by status
Active, not recruiting
1
Completed
13
Terminated
1
Trials led
TrialKey I/E criterionPhaseStatusEnrollment
Comparison of Two Treatment Regimens (Sitagliptin Versus Liraglutide) on Participants Who Failed to Achieve Good Glucose Control on Metformin Alone (MK-0431-403)HbA1c 7-11%Ph 3Completed653
A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013)HbA1c ≤9%Ph 2Completed381
A Preliminary Study of the Efficacy and Safety of MK-8521 for Type 2 Diabetes (MK-8521-004)BMI 23-40Ph 2Terminated176
A Study of Efinopegdutide (MK-6024) in Participants With Nonalcoholic Fatty Liver Disease (NAFLD) (MK-6024-001)BMI ≥25Ph 2Completed145
Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016)BMI ≥25Ph 2Completed124
Study of the Safety and Efficacy of MK-8521 Compared to Placebo and a Diabetes Drug in Participants With Type 2 Diabetes Mellitus (MK-8521-003)BMI 27-40Ph 1Completed87
A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)—Ph 2Active, not recruiting80
A Clinical Study of Efinopegdutide (MK-6024) in Healthy Chinese Volunteers (MK-6024-011)BMI 25-35Ph 1Completed56
A Study of Enlicitide Decanoate (MK-0616) and Semaglutide in Healthy Adult Participants (MK-0616-023)BMI 18-32Ph 1Completed38
A Study to Compare Methodologies for Assessing Glucose-Dependent Insulin Secretion (0000-104)(COMPLETED)BMI ≤26Ph 1Completed27
A Study of Efinopegdutide in Participants With Hepatic Impairment (MK-6024-014)Healthy volunteersPh 1Completed22
A Study That Will Evaluate Ketogenesis and Glucose-Dependent Insulin Secretion Methodologies in Healthy Male Subjects (MK-0000-159)(COMPLETED)BMI 27-35Ph 1Completed12