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StoryLCSS

Active not recruiting

Does Personality Predict Patient Adherence, Health Behaviors, and Weight Loss Outcomes During the Latino Crossover Semaglutide Study (LCSS)? (Story-LCSS Project)

Lead sponsor

Loma Linda University

Asset

Semaglutide

GLP-1 agonist

Listed sites

Recruiting sites

—

Enrollment

actual

Study population

Obesity / overweight

Key I/E criterion

—

Primary endpoints

•Predicted patient weight change success•Clinician predictions•Predicated patient calorie intake

Footprint

Where this trial recruits

Site locations as reported to ClinicalTrials.gov. Site count is not enrollment count; per-site enrollment is not available from source.

Identifiers

Registered as

NCT IDNCT05622045

Org study ID5220330

Timeline

Milestones

Study first posted2022-11-18actual

Study start2023-02-01actual

Primary completion2024-05-29actual

Last update posted2025-08-07actual

Study completion2026-05estimated (month precision)

Assets

Investigational agents

Semaglutide

Study populations

Who this study enrolls

Obesity / overweight

Eligibility

Who can enroll

Minimum age18 Years

Maximum age74 Years

SexAll

Sampling methodNon probability sample

Study population text

Hispanic men and women, 18 to 74 years of age, with obesity, residing in Southern California, who are taking part in the LCSS-Latino Crossover Semaglutide Study.

Inclusion criteria

•Participation in the LCSS-Latino Crossover Semaglutide Study

Exclusion criteria

•Not a participant of the LCSS-Latino Crossover Semaglutide Study at the point of data collection

Endpoints (6)

What's being measured

Protocol endpoints and posted registry outcome measures, grouped into outcome categories. Composite endpoints show their component event types. Standard codes (LOINC, SNOMED CT) are shown where available.

Coverage by outcome category

Other (unclassified)

Weight & body composition

1 endpoint

Primary/protocol endpoint/low confidence

Predicted patient weight change success

Time frame:The voice data measurement will take place at baseline and take about 10-15 minutes for collection to take place.

threshold achievement, improvement

Other (unclassified)

5 endpoints

Primary/protocol endpoint/low confidence

Clinician predictions

Time frame:The clinician judgement will be measured during the second month of the subject's weight loss study.

descriptive

Primary/protocol endpoint/low confidence

Predicated patient calorie intake

Time frame:The voice data measurement will take place during the subject's initial clinic visit and take about 10-15 minutes for collection to take place.

descriptive

Primary/protocol endpoint/low confidence

Predicated patient physical activity level

Time frame:The voice data measurement will take at baseline and take about 10-15 minutes for collection to take place.

descriptive

Secondary/protocol endpoint/low confidence

Personality attributes and values

Time frame:The voice data measurement will take place at baseline and take about 10-15 minutes for collection to take place.

descriptive

Secondary/protocol endpoint/low confidence

Predicted patient attrition rate

Time frame:The voice data measurement will take place at baseline and take about 10-15 minutes for collection to take place.

descriptive

Publications (7)

Bibliography

Records linked to this trial through ClinicalTrials.gov references, PubMed NCT search, and curated study seeds. 'Canonical' marks design/result papers; others are registry references or candidates.

Registry references + supporting bibliography

Use of Artificial Intelligence to understand adults' thoughts and behaviours relating to COVID-19.
Perspectives in public health2022 May (month)PMID33472547doi:10.1177/1757913920979332via CT.gov background
Disparate healthcare experiences of people living with overweight or obesity in England.
EClinicalMedicine2021 Nov (month)PMID34585130doi:10.1016/j.eclinm.2021.101140via CT.gov background
Once-Weekly Semaglutide in Adults with Overweight or Obesity.
The New England journal of medicine2021 Mar 18PMID33567185doi:10.1056/NEJMoa2032183via CT.gov background
Weight bias: a call to action.
Journal of eating disorders2016 (year)PMID27826445doi:10.1186/s40337-016-0112-4via CT.gov background
Overcoming Weight Bias in the Management of Patients With Diabetes and Obesity.
Clinical diabetes : a publication of the American Diabetes Association2016 Jan (month)PMID26807008doi:10.2337/diaclin.34.1.44via CT.gov background
Weight Loss Expectations and Attrition in Treatment-Seeking Obese Women.
Obesity facts2015 (year)PMID26444382doi:10.1159/000441366via CT.gov background
Effectiveness of a motivational interviewing intervention on weight loss, physical activity and cardiovascular disease risk factors: a randomised controlled trial with a 12-month post-intervention follow-up.
The international journal of behavioral nutrition and physical activity2013 Mar 28PMID23537492doi:10.1186/1479-5868-10-40via CT.gov background

Provenance

Sources

Trial identity, design, statusClinicalTrials.gov API v2

Snapshot dateJuly 1, 2026

Endpoint classificationDelfa endpoint taxonomy v2 (May 13, 2026)

Results tableno registry results posted yet

Trial facts come from public ClinicalTrials.gov records. Endpoint categories are Delfa's classification of those records, not a ClinicalTrials.gov field. All figures reflect the July 1, 2026 snapshot.