← Trials/Trial dossier/NCT06500130

CompletedPhase NA

Effects of Liraglutide on Body Surface Gastric Mapping

Lead sponsor

Alimetry

Assets

GLP-1 / incretin class catch-all / Liraglutide

Listed sites

1

Recruiting sites

Enrollment

22

actual

Study population

Healthy volunteers

Key I/E criteria

BMI 22-35Healthy volunteers

Primary endpoint

Overall postprandial BSGM Gastric Alimetry Rhythm Index (GA-RI) on treatment

Footprint

Where this trial recruits

Site locations as reported to ClinicalTrials.gov. Site count is not enrollment count; per-site enrollment is not available from source.

Identifiers

Registered as

NCT IDNCT06500130
Org study ID2024 FULL 19945

Timeline

Milestones

Study start2024-05-30actual
Study first posted2024-07-15actual
Primary completion2024-10-30actual
Study completion2024-11-30actual
Last update posted2025-01-29actual

Assets

Investigational agents

Study populations

Who this study enrolls

Healthy volunteers

Eligibility

Who can enroll

Minimum age18 Years
Maximum age65 Years
SexAll
Healthy volunteersAccepted

Inclusion criteria

Provision of signed and dated informed consent form, AND
Aged between 18 and 65 years old, AND
Healthy volunteer with no previous history of gastrointestinal disorders/symptoms
BMI 22-35

Exclusion criteria

1. Confirmed diagnosis of a comorbidity known to affect gastric motility (i.e., Parkinson\'s Disease, Type 1 or 2 Diabetes).

2. Medications in the last 3 months known to impact gastric motility.

3. Any Gastric Surgery

4. Pregnancy or lactation, determined by pregnancy test at timeof enrolment.

5. Known allergy to adhesives and/or skin sensitivities, or any allergy to liraglutide or any components of the liraglutide/Saxenda formulation, or known hypersensitivity to Spirulina, egg, milk or wheat allergens

6. Use of GLP-1 agonist and/or on regular insulin in the past 3months.

7. History of gastroduodenal dysfunction and/or meets the ROME IV symptom criteria for a gastroduodenal disorder of gut-brain interaction (functional dyspepsia, chronic nausea and vomiting syndrome, cyclic vomiting syndrome, rumination syndrome, cannabinoid hyperemesis syndrome, or a belching disorder).

8. History of peptic ulcer, pancreatitis, cholelithiasis, choledocholithiasis, History of kidney or hepatic dysfunction

9. History of psychiatric disturbance requiring medication in the year before enrolment, any history of suicide attempt or eating disorder

10. History of Type II Diabetes or glucose intolerance (treated or untreated)

11. History of cancer other than basal cell skin cancer, and patients with personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)

12. History of angioedema or urticaria disorder

13. History of cardiac disorder or arrhythmia

14. Any tobacco, vaping or cannabinoid use in the 30 days prior to study

Endpoints (10)

What's being measured

Protocol endpoints and posted registry outcome measures, grouped into outcome categories. Composite endpoints show their component event types. Standard codes (LOINC, SNOMED CT) are shown where available.

Coverage by outcome category

Other (unclassified)
9
Patient-reported / QoL
1

Patient-reported / QoL

1 endpoint
Secondary/protocol endpoint

Change in the following symptoms on treatment compared to baseline

Time frame:2 weeks

change from baseline, improvement

Other (unclassified)

9 endpoints
Primary/protocol endpoint/low confidence

Change in overall postprandial BSGM Gastric Alimetry Rhythm Index (GA-RI) on treatment compared to baseline.

Time frame:2 weeks

change from baseline, descriptive

Secondary/protocol endpoint/low confidence

Change in overall postprandial BMI-adjusted amplitude on treatment compared to baseline

Time frame:2 weeks

change from baseline, improvement

Secondary/protocol endpoint/low confidence

Change in GA-RI on treatment to washout

Time frame:1 week

change from baseline, descriptive

Secondary/protocol endpoint/low confidence

Change in BMI-adjusted amplitude on treatment to washout

Time frame:1 week

change from baseline, descriptive

Secondary/protocol endpoint/low confidence

Correlation of total symptom burden with change in GA-RI

Time frame:4 weeks

descriptive

Secondary/protocol endpoint/low confidence

Correlation of total symptom burden with change in BMI-adjusted amplitude

Time frame:4 weeks

descriptive

Secondary/protocol endpoint/low confidence

Change in gastric emptying half-time on treatment compared to baseline

Time frame:2 weeks

change from baseline, descriptive

Secondary/protocol endpoint/low confidence

Correlation of gastric emptying half-time with GA-RI on treatment

Time frame:2 weeks

descriptive

Secondary/protocol endpoint/low confidence

Correlation of gastric emptying half-time with total symptom burden on treatment

Time frame:2 weeks

descriptive

Provenance

Sources

Trial identity, design, statusClinicalTrials.gov API v2
Snapshot dateJuly 1, 2026
Endpoint classificationDelfa endpoint taxonomy v2 (May 13, 2026)
Results tableno registry results posted yet

Trial facts come from public ClinicalTrials.gov records. Endpoint categories are Delfa's classification of those records, not a ClinicalTrials.gov field. All figures reflect the July 1, 2026 snapshot.