← Trials/Trial dossier/NCT06500130
Effects of Liraglutide on Body Surface Gastric Mapping
Lead sponsor
Assets
GLP-1 / incretin class catch-all / Liraglutide
Listed sites
1
Recruiting sites
—
Enrollment
22
actual
Study population
Healthy volunteers
Key I/E criteria
•BMI 22-35•Healthy volunteers
Primary endpoint
•Overall postprandial BSGM Gastric Alimetry Rhythm Index (GA-RI) on treatment
Footprint
Where this trial recruits
Site locations as reported to ClinicalTrials.gov. Site count is not enrollment count; per-site enrollment is not available from source.
Identifiers
Registered as
Timeline
Milestones
Assets
Investigational agents
Study populations
Who this study enrolls
Eligibility
Who can enroll
Inclusion criteria
Exclusion criteria
1. Confirmed diagnosis of a comorbidity known to affect gastric motility (i.e., Parkinson\'s Disease, Type 1 or 2 Diabetes).
2. Medications in the last 3 months known to impact gastric motility.
3. Any Gastric Surgery
4. Pregnancy or lactation, determined by pregnancy test at timeof enrolment.
5. Known allergy to adhesives and/or skin sensitivities, or any allergy to liraglutide or any components of the liraglutide/Saxenda formulation, or known hypersensitivity to Spirulina, egg, milk or wheat allergens
6. Use of GLP-1 agonist and/or on regular insulin in the past 3months.
7. History of gastroduodenal dysfunction and/or meets the ROME IV symptom criteria for a gastroduodenal disorder of gut-brain interaction (functional dyspepsia, chronic nausea and vomiting syndrome, cyclic vomiting syndrome, rumination syndrome, cannabinoid hyperemesis syndrome, or a belching disorder).
8. History of peptic ulcer, pancreatitis, cholelithiasis, choledocholithiasis, History of kidney or hepatic dysfunction
9. History of psychiatric disturbance requiring medication in the year before enrolment, any history of suicide attempt or eating disorder
10. History of Type II Diabetes or glucose intolerance (treated or untreated)
11. History of cancer other than basal cell skin cancer, and patients with personal or family history of medullary thyroid carcinoma (MTC) or in patients with multiple endocrine neoplasia syndrome type 2 (MEN 2)
12. History of angioedema or urticaria disorder
13. History of cardiac disorder or arrhythmia
14. Any tobacco, vaping or cannabinoid use in the 30 days prior to study
Endpoints (10)
What's being measured
Protocol endpoints and posted registry outcome measures, grouped into outcome categories. Composite endpoints show their component event types. Standard codes (LOINC, SNOMED CT) are shown where available.
Coverage by outcome category
Patient-reported / QoL
1 endpointChange in the following symptoms on treatment compared to baseline
Time frame:2 weeks
change from baseline, improvement
Other (unclassified)
9 endpointsChange in overall postprandial BSGM Gastric Alimetry Rhythm Index (GA-RI) on treatment compared to baseline.
Time frame:2 weeks
change from baseline, descriptive
Change in overall postprandial BMI-adjusted amplitude on treatment compared to baseline
Time frame:2 weeks
change from baseline, improvement
Change in GA-RI on treatment to washout
Time frame:1 week
change from baseline, descriptive
Change in BMI-adjusted amplitude on treatment to washout
Time frame:1 week
change from baseline, descriptive
Correlation of total symptom burden with change in GA-RI
Time frame:4 weeks
descriptive
Correlation of total symptom burden with change in BMI-adjusted amplitude
Time frame:4 weeks
descriptive
Change in gastric emptying half-time on treatment compared to baseline
Time frame:2 weeks
change from baseline, descriptive
Correlation of gastric emptying half-time with GA-RI on treatment
Time frame:2 weeks
descriptive
Correlation of gastric emptying half-time with total symptom burden on treatment
Time frame:2 weeks
descriptive
Provenance
Sources
Trial facts come from public ClinicalTrials.gov records. Endpoint categories are Delfa's classification of those records, not a ClinicalTrials.gov field. All figures reflect the July 1, 2026 snapshot.