1. With my consent and signed informed consent, I am willing and able to complete this study in accordance with the requirements of the experimental protocol

2. Women aged 18-40 (including the threshold) on the date of signing the informed consent;

3. Patients who meet the diagnostic criteria for polycystic ovary syndrome;

4. Body mass index (BMI) ≥28 kg/m2;

5. Have controlled diet and exercise for at least 3 months, and the weight change is less than 5 kg

6. Within 2 months from the signing of the informed consent to the last drug use, there is no family planning and consent to take trial-approved contraceptive measures, and there is no egg donation plan

1. Endometrial biopsy is necessary as assessed by the investigators, and the pathology of the endometrial biopsy indicates significant abnormalities

2. 12-lead electrocardiogram (ECG) results showing clinically significant abnormalities that may affect the safety of the subject, including but not limited to myocardial infarction, severe arrhythmias (e.g., supraventricular tachycardia, atrial fibrillation, atrial flutter, degree II or III atrioventricular block, etc.), and QTcF > 470 ms

3. Poor blood pressure control (with or without antihypertensive therapy) : systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥100 mmHg at screening

4. PHQ-9 score ≥15 points

5. The presence of endocrine disorders or medical history that may significantly affect body weight

6. Presence of other medical conditions or history that may cause hyperandrostenia or irregular menstruation

7. Presence of a history of gynecological conditions that may affect the evaluation of menstruation (including, but not limited to, history of hysterectomy, vaginal atresia, uterine adhesions)

8. Abnormal uterine bleeding for reasons other than PCOS or unexplained abnormal uterine bleeding occurred within 6 months

9. Endometrium-related surgery within 1 year indicated significant pathological abnormalities of endometrial tissue, and safety risks were assessed by researchers

10. History of pregnancy, miscarriage, childbirth or breastfeeding within 6 months

11. Have any disease or history that affects gastric empty. such as gastric bypass surgery, pyloric stenosis, etc., long-term use of drugs that directly affect gastrointestinal motility, serious gastrointestinal disease (such as active peptic ulcer, inflammatory bowel disease, etc.), or have undergone gastrointestinal surgery (except surgery that has no significant effect on gastrointestinal motility), Such as gastrointestinal polypectomy, appendectomy and hemorrhoid surgery);

12. A history or disease of acute or chronic pancreatitis or pancreatic injury; Patients with a history of acute cholecystitis or symptomatic/treatable gallbladder disease (except those who had previously undergone cholecystectomy and were deemed eligible by the investigator to be enrolled);

13. History or family history of medullary thyroid carcinoma (MTC) or multiple endocrine adenomatosis type 2 (MEN2);

14. Severe infection, severe trauma, or major or major surgery in the previous 6 months

15. A history of severe cardiovascular and cerebrovascular disease, including decompensated heart failure (New York Heart Association ratings III and IV), unstable angina pectoris, stroke or transient ischemic attack, myocardial infarction, severe arrhythmia, or coronary bypass grafting or percutaneous coronary intervention within the previous 6 months;

16. Any organ-system malignancy within the previous 5 years, regardless of evidence of local recurrence or metastasis, except cured local basal cell carcinoma of the skin, cervical carcinoma in situ, and prostate carcinoma in situ;

17. Present or suspected depression, anxiety disorder, bipolar disorder, suicidal tendencies, schizophrenia, or other more serious mental illness

18. A known or suspected history of alcohol and/or drug abuse or drug use

19. A history of acute or chronic hepatitis, or other serious liver disease other than alcoholic fatty liver disease;

20. A history of unstable or rapidly progressing kidney disease or end-stage kidney disease

21. Autoimmune disease is present and systemic glucocorticoid therapy or immunosuppressive therapy is planned for the study period;

22. Participated in a clinical trial of any drug or medical device within the previous 3 months, defined as signing informed consent and using the investigational drug (including placebo) or the investigational medical device; Or is still in the trial drug within 5 half-lives (whichever is older);

23. Those who have donated blood or lost blood ≥400 mL in the previous 3 months, or received blood transfusion

24. Surgery is planned during the trial period (except for minor surgery that the investigator believes will not affect the trial);

25. Mentally incapacitated or speech-impaired subjects are unable to fully understand or participate in the test process;

26. Researchers and relevant staff of the research Centre or others directly involved in the implementation of the programme, as well as members of their immediate family (e.g. spouse, legal partner, parents, children or siblings); Hengrui company staff;

27. There are circumstances (medical, psychological, social or geographical factors, etc.) that, in the investigator's judgment, affect the subject's safety or any other conditions that interfere with the evaluation of the test results.