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aGLP1-GUS

Not yet recruiting

Gastric Emptying in Healthy Volunteers and GLP-1 Agonist Users

Gastric Emptying Assessed by Gastric Ultrasound (US) in Healthy Volunteers and Semaglutide Users: Cohort Study

Lead sponsor

Clinica Alemana de Santiago

Assets

GLP-1 / incretin class catch-all / Semaglutide

Listed sites

Recruiting sites

—

Enrollment

155

estimated

Study population

Healthy volunteers, Perioperative / gastric aspiration risk

Key I/E criterion

•Healthy volunteers

Primary endpoint

•Each Grade according Perlas et al

Identifiers

Registered as

NCT IDNCT06987669

Org study IDID1406

Secondary ID2024-100Comité Etico Cientifico Facultad de Medicina Universidad del Desarrollo Clínica Alemana

Timeline

Milestones

Study start2025-05-17estimated

Study first posted2025-05-23actual

Last update posted2025-05-23actual

Primary completion2026-12-31estimated

Study completion2027-12-31estimated

Assets

Investigational agents

GLP-1 / incretin class catch-all Semaglutide

Study populations

Who this study enrolls

Healthy volunteersPerioperative / gastric aspiration risk

Eligibility

Who can enroll

Minimum age18 Years

SexAll

Healthy volunteersAccepted

Sampling methodNon probability sample

Study population text

Healthy volunteers will be assessed for emptying the stomach after a standardized high-fat meal, by ultrasound. Cohort of patients on a GLP-1 agonist after 18/24 hours of clear fluids.

Inclusion criteria

•18 years old or older

•Healthy volunteers or semaglutide users

Exclusion criteria

•Bariatric surgery

•Hiatal hernia

•Impairment to give consent

Endpoints (2)

What's being measured

Protocol endpoints and posted registry outcome measures, grouped into outcome categories. Composite endpoints show their component event types. Standard codes (LOINC, SNOMED CT) are shown where available.

Other clinical outcomes

2 endpoints

Primary/protocol endpoint

Number of patients with each Grade ( stomach content characteristics) according Perlas et al

Time frame:24 hours tops since the starting of the clear fluid diet

categorical status, descriptive

Secondary/protocol endpoint

Area of the stomach in supine and in RLD assessed by ultrasound

Time frame:24 hours tops since the starting of the clear fluid diet

categorical status, descriptive

Provenance

Sources

Trial identity, design, statusClinicalTrials.gov API v2

Snapshot dateJuly 1, 2026

Endpoint classificationDelfa endpoint taxonomy v2 (May 13, 2026)

Results tableno registry results posted yet

Trial facts come from public ClinicalTrials.gov records. Endpoint categories are Delfa's classification of those records, not a ClinicalTrials.gov field. All figures reflect the July 1, 2026 snapshot.