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Tirzepatide
Not yet recruitingPhase NAEfficacy and Safety of Tirzepatide (Spartina) in Chronic Kidney Failure
Safety and Effectiveness of Tirzepatide(Spartina )in Chronic Kidney Failure a Single-center Study
Lead sponsor
Asset
Tirzepatide
Subcutaneous · GLP-1 / GIP dual
Listed sites
1
Recruiting sites
—
Enrollment
15
estimated
Study population
Chronic kidney disease, Diabetes (other / unspecified), Obesity / overweight
Key I/E criterion
•BMI ≥27
Primary endpoint
•Body weight, absolute change (kg)
Footprint
Where this trial recruits
Site locations as reported to ClinicalTrials.gov. Site count is not enrollment count; per-site enrollment is not available from source.
Identifiers
Registered as
Timeline
Milestones
Assets
Investigational agents
Study populations
Who this study enrolls
Eligibility
Who can enroll
Inclusion criteria
age ≥18 years and history of diabetes or BMI over 27
Exclusion criteria
Previous usage of similar therapy for less than 3 months owing to the inability to capture all efficacy and safety endpoints within this brief timeframe and/or nonadherence to tirzepatide therapy
Endpoints (1)
What's being measured
Protocol endpoints and posted registry outcome measures, grouped into outcome categories. Composite endpoints show their component event types. Standard codes (LOINC, SNOMED CT) are shown where available.
Weight & body composition
1 endpointweight loss
Time frame:kilogram of weight loss measured by same scale one and three month after injection
Body weight, absolute change (kg)
change from baseline, improvement
Publications (10)
Bibliography
Records linked to this trial through ClinicalTrials.gov references, PubMed NCT search, and curated study seeds. 'Canonical' marks design/result papers; others are registry references or candidates.
Registry references + supporting bibliography
- The New England journal of medicine2025 Dec 18PMID41406444doi:10.1056/NEJMoa2505928via pubmed acronym asset candidate
- The New England journal of medicine2025 Jul 3PMID40353578doi:10.1056/NEJMoa2416394via pubmed acronym asset candidate
- JAMA internal medicine2024 Sep 1PMID38976257doi:10.1001/jamainternmed.2024.2525via pubmed acronym asset candidate
- The New England journal of medicine2024 Jul 25PMID38856224doi:10.1056/NEJMoa2401943via pubmed acronym asset candidate
- American heart journal2024 Jan (month)PMID37758044doi:10.1016/j.ahj.2023.09.007via pubmed acronym asset candidate
- The lancet. Diabetes & endocrinology2022 Jun (month)PMID35468322doi:10.1016/S2213-8587(22)00085-7via pubmed acronym asset candidate
- The New England journal of medicine2021 Aug 5PMID34170647doi:10.1056/NEJMoa2107519via pubmed acronym asset candidate
- Lancet (London, England)2021 Jul 10PMID34186022doi:10.1016/S0140-6736(21)01324-6via pubmed acronym asset candidate
Provenance
Sources
Trial facts come from public ClinicalTrials.gov records. Endpoint categories are Delfa's classification of those records, not a ClinicalTrials.gov field. All figures reflect the July 1, 2026 snapshot.