| NCT00838110A Phase 3 Study To Evaluate The Safety And Tolerability Of Dimebon Patients With Mild To Moderate Alzheimer's Disease | Dimebon Alzheimer’s disease | Alzheimer's disease | Ph 3 | Completed | 118 | Jan 2010 | - | results |
| NCT00939783An Extension To The B1451027 Protocol To Evaluate The Long Term Safety And Tolerability Of Dimebon In Patients With Alzheimer's Disease | Dimebon Alzheimer’s disease | Age ≥50 | Ph 3 | Terminated | 105 | Aug 2010 | - | results |
| CONCERTSafety and Efficacy Study Evaluating Dimebon in Patients With Mild to Moderate Alzheimer's Disease on Donepezil | Dimebon Alzheimer’s disease | mild-to-moderate AD | Ph 3 | Completed | 101 | Dec 2011 | - | |
| NCT00912288A Phase 3 Efficacy Study Of Dimebon In Patients With Moderate To Severe Alzheimer's Disease | Dimebon Alzheimer’s disease | Study partner/caregiver required | Ph 3 | Terminated | 47 | Aug 2010 | - | results |
| CONNECTIONA Safety and Efficacy Study of Oral Dimebon in Patients With Mild-To-Moderate Alzheimer's Disease | Dimebon Alzheimer’s disease | mild-to-moderate AD | Ph 3 | Completed | 28 | Dec 2009 | - | |
| NCT07251023Efficacy and Safety of DMB-I (INN: Latrepirdine) in Patients With Alzheimer Type Dementia | Dimebon, Memantine Alzheimer’s disease | mild-to-moderate AD | Ph 3 | Recruiting | 12 | May 2027 | - | |
| NCT06292351DMB-I in the Treatment of Alzheimer Type Dementia | Dimebon Alzheimer’s disease | mild-to-moderate AD | Ph 2 | Completed | 7 | Jan 2025 | 1 | |
| NCT01066546An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease | Dimebon Alzheimer’s disease | Age ≥50 | Ph 3 | Terminated | 5 | Jul 2010 | - | results |
| NCT00704782Study of Combination Therapy With Dimebon and Donepezil (Aricept) in Patients With Alzheimer's Disease | Dimebon Alzheimer’s disease | Alzheimer's disease | Ph 2 | Terminated | 4 | Aug 2010 | - | |
| NCT00829816Safety and Tolerability of Dimebon in Patients on Memantine, and Memantine Plus Donepezil | Dimebon Alzheimer’s disease | Alzheimer's disease | Ph 1 | Completed | 4 | Apr 2009 | - | |
| CONTACTA Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease | Dimebon Alzheimer’s disease | MMSE 5-14 | Ph 3 | Terminated | 2 | Aug 2010 | - | |
| NCT00824590A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function | Dimebon Alzheimer’s disease | Healthy volunteers | Ph 1 | Completed | 2 | Oct 2009 | - | |
| NCT00827034A Phase 1, Randomized, Open-Label, Two-Way Crossover Study To Evaluate The Steady-State Effect Of Dimebon (PF 01913539) On The Single-Dose Pharmacokinetics And Pharmacodynamics Of Warfarin In Healthy Subjects | Dimebon Alzheimer’s disease | Age 18-55 | Ph 1 | Completed | 1 | Apr 2009 | - | |
| NCT00788047A Phase 1 Study To Evaluate The Effect Of Dimebon On The Pharmacokinetics Of Dextromethorphan | Dimebon Alzheimer’s disease | Age 18-55 | Ph 1 | Completed | 1 | Jan 2009 | - | |
| NCT00990613A Study Evaluating The Absorption Of Dimebon Into The Body From A Dimebon Solution Applied To The Skin | Dimebon Alzheimer’s disease | Age 50-85 | Ph 1 | Completed | 1 | Jan 2010 | 1 | |
| NCT00931073A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers | Dimebon Alzheimer’s disease | Age 18-55 | Ph 1 | Completed | 1 | Oct 2009 | - | |
| NCT00825084A Phase 1 Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF-01913539] In Japanese And Western Healthy Subjects | Dimebon Alzheimer’s disease | Age 18-55 | Ph 1 | Completed | 1 | May 2009 | - | |
| NCT00988624A Study In Healthy Volunteers To Estimate The Pharmacokinetics Of Four Modified-Release Formulations Of Dimebon (Latrepirdine) | Dimebon Alzheimer’s disease | Age 18-55 | Ph 1 | Completed | 1 | Dec 2009 | - | |
| NCT00377715Double-blind, Placebo-controlled Study of Oral Dimebon in Subjects With Mild to Moderate Alzheimer's Disease | Dimebon Alzheimer’s disease | Alzheimer's disease | Ph 2 | Completed | 1 | Aug 2006 | 1 | |
| NCT00831506Dimebon (PF-01913539)-Digoxin Drug-Drug Interaction Study In Healthy Subjects | Dimebon Alzheimer’s disease | Age 18-55 | Ph 1 | Completed | 1 | May 2009 | - | |
| NCT01066481A Study Of Oral PF-01913539 In Patients With Mild To Moderate Alzheimer's Disease | Dimebon Alzheimer’s disease | mild-to-moderate AD | Ph 2 | Withdrawn | 0 | Mar 2012 | - | |
| NCT00975481A Study To Evaluate The Abuse Potential Of Single Oral Doses Of Dimebon (Latrepirdine) In Healthy Recreational Polydrug Users | Dimebon Alzheimer’s disease | Age 18-55 | Ph 1 | Completed | 0 | Feb 2010 | - | results |
| CONCERT PLUSAn Extension of the CONCERT Protocol (DIM18) | Dimebon Alzheimer’s disease | mild-to-moderate AD | Ph 3 | Terminated | 0 | May 2012 | - | |
