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Nilotinib

4 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

4

Ongoing

0

Recruiting

0

Completed

3

Sites

2

Countries

1

Endpoints

45

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 45 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
1
Phase 2
2
Phase 3
1

Trials by status

Completed
3
Unknown
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Global cognition
8
Behavior / neuropsychiatric
8
Fluid / digital biomarkers
6
Safety / tolerability / PK
5
Executive function / language
4
Amyloid biomarkers
4
Function / daily living
3
Tau biomarkers
3
Other clinical outcomes
2
Other (unclassified)
2

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 15 of 45 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

ADCS-Activities of Daily Living (ADCS-ADL)Function

3

ADAS-CogCognition

3

Montreal Cognitive Assessment (MoCA)Cognition

2

ADAS-CogOther

2

Neuropsychiatric Inventory (NPI)Behavior

2

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

2

Mini-Mental State Examination (MMSE)Cognition

1

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

4 of 4

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT04002674Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies

Nilotinib

Lewy body dementia

Dementia with Lewy bodiesPh 2Completed1Apr 20251results
NCT02281474Nilotinib in Cognitively Impaired Parkinson Disease Patients 001

Nilotinib

Lewy body dementia

MMSE 23-30Ph 1Completed1May 20151
ADImpact of Nilotinib on Safety, Biomarkers and Clinical Outcomes in Mild to Moderate Alzheimer's Disease

Nilotinib

Alzheimer’s disease

mild-to-moderate ADPh 2Completed1Dec 20202
NILEADEvaluating the Efficacy and Safety of Nilotinib BE in Subjects With Early Alzheimer's Disease

Nilotinib

Alzheimer’s disease

Alzheimer's diseasePh 3Unknown0Dec 20251

Showing 1-4 of 4 trials