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TB006

4 trials in this asset. Source: ClinicalTrials.gov, as of July 21, 2026.

Trials

4

Ongoing

0

Recruiting

0

Completed

2

Sites

20

Countries

1

Endpoints

167

Composite endpoints

0

Distinct sites and countries across this asset's trials. A site running several of its trials counts once, matching the map. All 167 linked ClinicalTrials.gov endpoints are classified into the categories below. Trial and endpoint linkage does not by itself establish treatment attribution for every endpoint.

Development

Where the program stands

Trials by phase

Phase 1
1
Phase 1/2
1
Phase 2
1
Not applicable
1

Trials by status

Completed
2
Terminated
1
Unknown
1

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Other (unclassified)
81
Safety / tolerability / PK
57
Global cognition
12
Behavior / neuropsychiatric
12
Executive function / language
4
Fluid / digital biomarkers
1

Most-measured metrics

Top 20 metrics across this asset's endpoints

Normalized metric codes are available for 16 of 167 classified ClinicalTrials.gov endpoints for this asset; the ranking below covers that coded subset.

Clinical Dementia Rating-Sum of Boxes (CDR-SB)Cognition

8

Mini-Mental State Examination (MMSE)Cognition

4

Neuropsychiatric Inventory (NPI)Behavior

4

Trials

Trials for this asset

Every trial for this asset, with the same search, filters, and sort as the Trials tab.

4 of 4

Alzheimer’s disease and related dementias trials
Asset / Disease areaKey I/E criterionEvidence
NCT05074498Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of TB006 in Participants With Alzheimer's Disease

TB006

Alzheimer’s disease

Alzheimer's diseasePh 1/2Completed18Oct 2022-results
NCT05476783A Long Term Extension Study to Assess the Safety of TB006 in Participants With Alzheimer's Disease

TB006

Alzheimer’s disease

Alzheimer's diseasePh 2Terminated13Nov 2023-results
TB006SADSequential Dose-escalation Study to Assess the Safety, Tolerability and Pharmacokinetics of TB006 in Healthy Subjects

TB006

Alzheimer’s disease

Healthy volunteersPh 1Completed1May 2022-
NCT05959239TB006 Expanded Access (EA) Compassionate Use

TB006

Alzheimer’s disease

Alzheimer's diseaseNot applicableUnknown0--

Showing 1-4 of 4 trials