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Post-marketing Surveillance of Donepezil Hydrochloride -Investigation of the Clinical Safety and Effectiveness in Patients With Alzheimer's Disease

Post-marketing Surveillance of Donepezil Hydrochloride- Investigation of the Clinical Safety and Effectiveness in Patients With Alzheimer's Disease

Lead sponsor

Eisai Co., Ltd.

Asset

Donepezil

Listed sites

106

Recruiting sites

-

Enrollment

894

actual

Study population

Alzheimer’s disease

Key I/E criterion

Age ≥18

Primary endpoint

ADAS-Jcog

Footprint

Where this trial recruits

Site locations as reported to ClinicalTrials.gov. Site count is not enrollment count; per-site enrollment is not available from source.

Identifiers

Registered as

Org study IDART06T
NCT IDNCT01251718

Timeline

Milestones

Study start2010-12-01actual
Study first posted2010-12-02estimated
Primary completion2015-10-14actual
Study completion2016-02-18actual
Last update posted2023-07-24actual

Assets

Drug assets

Study populations

Who this study enrolls

Alzheimer’s disease

Eligibility

Who can enroll

Minimum age18 Years
SexAll
Healthy volunteersNot accepted

Inclusion criteria

Patients diagnosed as Alzheimer's Disease by Diagnostic and Statistical Manual of Mental Disorders (DSM-IV).

Patients diagnosed as mild or moderate Alzheimer's Disease, applicable to Functional Assessment Staging (FAST) score 4 or 5

Exclusion criteria

Patients who used Aricept within 3 months prior to dosing.

Patients registered this survey before.

Patients with a history of hypersensitivity to any ingredients of Aricept or piperidine derivatives.

Endpoints (2)

What's being measured

Protocol endpoints and posted registry outcome measures, grouped into outcome categories. Composite endpoints show their component event types. Standard codes (LOINC, SNOMED CT) are shown where available.

Coverage by outcome category

Global cognition
1
Safety / tolerability / PK
1

Global cognition

1 endpoint
Primary/protocol endpoint

ADAS-Jcog (test of cognitive function)

Time frame:36 month (12 weeks and every 6 months)

descriptive

Safety / tolerability / PK

1 endpoint
Secondary/protocol endpoint

Adverse events/adverse drug reactions

Time frame:36 months

event count, event

Provenance

Sources

Trial identity, design, statusClinicalTrials.gov API v2
Snapshot dateJuly 21, 2026
Endpoint classificationDelfa ADRD endpoint taxonomy
Results tableno registry results posted yet

Trial facts come from public ClinicalTrials.gov records. Endpoint categories are Delfa's classification of those records, not a ClinicalTrials.gov field. All figures reflect the July 21, 2026 snapshot.