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Subcutaneous · GLP-1 / GIP / glucagon triple

UBT251

8 trials in this molecule. Source: ClinicalTrials.gov, as of July 1, 2026.

Trials

8

Active

6

Recruiting

3

Completed

2

Sites

9

Countries

3

Endpoints

100

Composite endpoints

1

Distinct sites and countries across this molecule's trials. A site running several of its trials counts once, matching the map.

Development

Where the program stands

Trials by phase

Phase 2
5
Phase 3
3

Trials by status

Not yet recruiting
3
Recruiting
3
Completed
2

Evidence coverage

What this asset has been measured on

Endpoints grouped into outcome categories, ranked by how often they are measured across this asset's trials.

Weight & body composition
23
Glycemic / diabetes
21
Cardiometabolic biomarkers
15
MASH / liver
13
Safety / tolerability / PK
11
Other (unclassified)
9
Renal / kidney
5
Patient-reported / QoL
3

Most-measured metrics

Top 20 metrics across this asset's endpoints

HbA1c, changeGlycemic

2

Fasting glucose, changeGlycemic

2

Postprandial glucoseGlycemic

1

Body weight, absolute change (kg)Weight

1

Waist circumference, changeWeight

1

HbA1c <7.0% achievementGlycemic

1

HbA1c <6.5% achievementGlycemic

1

Systolic BP, changeBiomarker

1

Diastolic BP, changeBiomarker

1

Trials

Programs for this asset

Every trial for this molecule, with the same search, filters, and sort as the Trials tab.

8 of 8

Asset / PopulationKey I/E criterionEvidence
NCT07395687A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity

UBT251

Obesity / overweight

Ph 2Recruiting3Jan 2027
T2DMUBT251 Injection Phase II (Type 2 Diabetes Mellitus) Study

Semaglutide, UBT251

Type 2 diabetes

BMI 23-40Ph 2Completed1Nov 2025
MASHA Study of UBT251 in Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH)

UBT251

MASH / NAFLD / liver fibrosis

BMI ≥24Ph 2Recruiting1Jun 2027
NCT07177469UBT251 Injection Phase II Study (Overweight or Obesity)

UBT251

Obesity / overweight

BMI ≥28Ph 2Completed1Oct 2025
NCT07648225UBT251 Injection Phase Ⅲ Study (Overweight or Obesity)

UBT251

Obesity / overweight

BMI ≥28Ph 3Not yet recruiting1Sep 2027
NCT07134335UBT251 Injection Phase II Clinical Study (CKD)

UBT251

Chronic kidney disease, Obesity / overweight

BMI ≥24Ph 2Recruiting1Jul 2030
UNIGUIDE-1Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control on Diet and Exercise Alone(UNIGUIDE-1)

UBT251

Obesity / overweight, Type 2 diabetes

BMI ≥23Ph 3Not yet recruiting1Sep 2027
UNIGUIDE-2Phase III Study of UBT251 Injection in Patients With Type 2 Diabetes With Inadequate Glycemic Control on Metformin ± Sulfonylurea/SGLT2 Inhibitor Therapy (UNIGUIDE-2)

Semaglutide, UBT251

Obesity / overweight, Type 2 diabetes

BMI ≥23Ph 3Not yet recruiting0Feb 2028