1. The patient volunteers and signs an informed consent form.

2. age ≥18 and ≤75 years old;

3. Patients with hypoglycaemia in the presence of neuroglycopenic symptoms and documented Whipple's triad;

4. Biochemically proven endogenous hyperinsulinemic hypoglycaemia (plasma glucose concentration <3.0 mM, insulin >3 µU/ml, and C-peptide >0.6 ng/ml);

5. Conventional imaging within 3 month.

1. Having a history of allergy to similar drugs, allergic constitution or suffering from allergic diseases;

2. Breast feeding;

3. Pregnancy or the wish to become pregnant within 6 months;

4. Renal function: serum creatinine > 3.0 mg/dl;

5. Any medical condition that, in the opinion of the investigator, may significantly interfere with study compliance.